Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.40 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.38 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.38 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.38 |
| ▸ | MPO | P05164 | 2/20 | 0.38 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.35 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | AURKA | O14965 | 1/20 | 0.35 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | GLA | P06280 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18635648 | 0.72 | KMT2A (0.39) | FFAR4HDAC4KMT2AMEN1CYP3A4 | |
| SCHEMBL5075669 | 0.71 | FFAR4 (0.40) | FFAR4MPOHDAC4AURKAGAA | |
| SCHEMBL15637823 | 0.70 | SMN1; SMN2 (0.50) | MPOKMT2AMEN1AKR1C3 | |
| SCHEMBL16986482 | 0.69 | CES2 (0.38) | HDAC4KMT2AMEN1P2RX7 | |
| SCHEMBL9314416 | 0.68 | ALDH1A1 (0.41) | CYP4F2CYP4A11KMT2AMEN1TAAR1 | |
| SCHEMBL1337385 | 0.68 | FFAR4 (0.47) | FFAR4CYP4F2CYP4A11KMT2AMEN1 | |
| SCHEMBL5075668 | 0.68 | KDM4E (0.52) | — | |
| SCHEMBL7635281 | 0.67 | MTNR1A (0.51) | KMT2AMEN1NPC1RAB9A | |
| SCHEMBL8258560 | 0.67 | MTNR1A (0.52) | KMT2AMEN1GAATAAR1NPC1 | |
| Formic Acid SCHEMBL5076825 | 0.67 | ALDH1A1 (0.41) | MPOHPGDKMT2AMEN1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2903998-A1 | IAP ANTAGONISTS | Bristol-Myers Squibb Company (US) | 2015-08-12 | — | — | EP | disclosed |