SCHEMBL16992178

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL19974288	0.95	NPC1 (0.43)	NPC1RAB9ASMN1; SMN2L3MBTL1L3MBTL3
	SCHEMBL15533257	0.95	NPC1 (0.43)	NPC1RAB9ASMN1; SMN2L3MBTL1L3MBTL3
	SCHEMBL6806462	0.87	L3MBTL3 (0.41)	NPC1RAB9ASMN1; SMN2L3MBTL1L3MBTL3
	SCHEMBL1419834	0.87	NPC1 (0.47)	NPC1RAB9ASMN1; SMN2L3MBTL1TDP1
	SCHEMBL18241087	0.84	L3MBTL1 (0.39)	NPC1RAB9ASMN1; SMN2L3MBTL1L3MBTL3
	Hydrochloric Acid SCHEMBL28414182	0.83	L3MBTL3 (0.38)	NPC1RAB9ASMN1; SMN2L3MBTL1L3MBTL3
	SCHEMBL2824467	0.83	NPC1 (0.56)	NPC1RAB9ASMN1; SMN2L3MBTL1TDP1
	SCHEMBL385345	0.79	NPC1 (0.51)	NPC1RAB9ASMN1; SMN2L3MBTL3TDP1
	SCHEMBL13254845	0.79	NPC1 (0.51)	NPC1RAB9ASMN1; SMN2L3MBTL3TDP1
	SCHEMBL3169796	0.79	NPC1 (0.51)	NPC1RAB9ASMN1; SMN2L3MBTL1L3MBTL3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (9 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.