Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL3 | Q96JM7 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | CA2 | P00918 | 1/20 | 0.38 |
| ▸ | CHKA | P35790 | 1/20 | 0.38 |
| ▸ | CNR2 | P34972 | 1/20 | 0.36 |
| ▸ | HSD11B1 | P28845 | 5/20 | 0.36 |
| ▸ | HSD17B1 | P14061 | 1/20 | 0.35 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.35 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.35 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.35 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.35 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.35 |
| ▸ | WDR77 | Q9BQA1 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16992178 | 0.87 | NPC1 (0.42) | L3MBTL3L3MBTL1NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL18241087 | 0.86 | L3MBTL1 (0.39) | L3MBTL3L3MBTL1NPC1RAB9ASMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL28414182 | 0.84 | L3MBTL3 (0.38) | L3MBTL3L3MBTL1NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL794610 | 0.82 | NPC1 (0.53) | L3MBTL3L3MBTL1NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL19974288 | 0.81 | NPC1 (0.43) | L3MBTL3L3MBTL1NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL15533257 | 0.81 | NPC1 (0.43) | L3MBTL3L3MBTL1NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL30032926 | 0.78 | NR1H2 (0.43) | NPC1HPGDEPHX1 | |
| SCHEMBL22130580 | 0.76 | NPC1 (0.46) | L3MBTL3L3MBTL1NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL3932469 | 0.76 | GAA (0.35) | L3MBTL3L3MBTL1NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL28421387 | 0.75 | L3MBTL3 (0.37) | L3MBTL3L3MBTL1TDP1GAAEPHX1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040039040-A1 | Urea derivative and adhesive-molecule inhibitor containing the same as active ingredient | TORAY INDUSTRIES, INC. (JP) | 2004-02-26 | — | — | US | disclosed |
| EP-1323709-A1 | UREA DERIVATIVE AND ADHESIVE-MOLECULE INHIBITOR CONTAINING THE SAME AS ACTIVE INGREDIENT | TORAY INDUSTRIES, INC. (JP) | 2003-07-02 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040039040-A1 | Urea derivative and adhesive-molecule inhibitor containing the same as active ingredient | ICAM1, VCAM1, EPCAM | L3MBTL3 4866/4885L3MBTL1 4736/4885NPC1 3824/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.