Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.39 |
| ▸ | NCF1 | P14598 | 13/20 | 0.39 |
| ▸ | HSP90AA1 | P07900 | 4/20 | 0.38 |
| ▸ | HSP90AB1 | P08238 | 2/20 | 0.37 |
| ▸ | BACE1 | P56817 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4264916 | 0.73 | XDH (0.46) | L3MBTL1NCF1 | |
| SCHEMBL13952547 | 0.68 | XDH (0.51) | L3MBTL1 | |
| SCHEMBL17281786 | 0.67 | KDM4E (0.43) | L3MBTL1 | |
| SCHEMBL19295640 | 0.65 | RAB9A (0.47) | NCF1 | |
| 1,2-Dichlorobenzene SCHEMBL27546533 | 0.64 | LMNA (0.50) | L3MBTL1 | |
| SCHEMBL26236027 | 0.64 | MAPT (0.42) | L3MBTL1 | |
| SCHEMBL11522755 | 0.63 | APP (0.57) | L3MBTL1 | |
| SCHEMBL12703813 | 0.63 | LTA4H (0.44) | — | |
| SCHEMBL12012137 | 0.63 | APP (0.57) | L3MBTL1 | |
| SCHEMBL12012139 | 0.63 | APP (0.57) | L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015118110-A1 | PYRIDO[2,3-D]PYRIMIDINE-7(8H)-ONE DERIVATIVES FOR THE TREATMENT OF HEPATITIS C | INSTITUT QUÍMIC DE SARRIÁ, CETS FUNDACIÓ PRIVADA (ES) | 2015-08-13 | — | — | WO | disclosed |