Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE10A | Q9Y233 | 6/20 | 0.36 |
| ▸ | DRD1 | P21728 | 5/20 | 0.35 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.33 |
| ▸ | USP1 | O94782 | 4/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.31 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.31 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.31 |
| ▸ | MAP3K11 | Q16584 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1699111 | 0.90 | PDE10A (0.36) | PDE10ADRD1PDE4BLMNA | |
| SCHEMBL1699098 | 0.81 | DRD1 (0.44) | PDE10ADRD1PDE4BLMNAHDAC1 | |
| SCHEMBL1699084 | 0.80 | DRD1 (0.39) | PDE10ADRD1PDE4BLMNAHDAC1 | |
| SCHEMBL1699250 | 0.80 | PDE10A (0.36) | PDE10ADRD1PDE4BLMNAHDAC1 | |
| SCHEMBL1699248 | 0.79 | DRD1 (0.38) | PDE10ADRD1PDE4BLMNAHDAC1 | |
| SCHEMBL1699092 | 0.79 | DRD1 (0.38) | PDE10ADRD1PDE4BLMNAHDAC1 | |
| SCHEMBL14889112 | 0.78 | DRD1 (0.38) | PDE10ADRD1PDE4BLMNA | |
| SCHEMBL1699557 | 0.76 | HDAC1 (0.37) | PDE10ADRD1USP1LMNAHDAC1 | |
| SCHEMBL1699185 | 0.74 | NPC1 (0.50) | — | |
| SCHEMBL9981648 | 0.73 | PDE10A (0.41) | PDE10APDE4BLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011163355-A1 | FUSED HETEROCYCLIC COMPOUNDS AS PHOSPHODIESTERASES (PDES) INHIBITORS | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2011-12-29 | — | — | WO | disclosed |