Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDGFRA | P16234 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | BCL3 | P20749 | 1/20 | 0.38 |
| ▸ | CDK2 | P24941 | 6/20 | 0.37 |
| ▸ | CCNA2 | P20248 | 5/20 | 0.37 |
| ▸ | CDK1 | P06493 | 3/20 | 0.37 |
| ▸ | CCNB1 | P14635 | 3/20 | 0.37 |
| ▸ | CCNA1 | P78396 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8215154 | 0.94 | BCL3 (0.43) | PDGFRAHPGDBCL3CDK2CCNA2 | |
| SCHEMBL16995287 | 0.79 | CDK2 (0.45) | CDK2CCNA2CDK1CCNB1 | |
| SCHEMBL16995307 | 0.77 | HTR4 (0.45) | BCL3CDK2CCNA2CDK1CCNB1 | |
| SCHEMBL8226199 | 0.75 | CCNA2 (0.53) | BCL3CDK2CCNA2CDK1CCNB1 | |
| SCHEMBL13543788 | 0.75 | CCNA2 (0.48) | KMT2ABCL3CDK2CCNA2CDK1 | |
| SCHEMBL8219161 | 0.74 | CCNA2 (0.63) | MEN1KMT2ACDK2CCNA2CDK1 | |
| SCHEMBL16995302 | 0.74 | L3MBTL1 (0.48) | MEN1KMT2ACDK2CCNA2CDK1 | |
| SCHEMBL8261337 | 0.74 | CCNA2 (0.57) | MEN1KMT2ACDK2CCNA2CDK1 | |
| SCHEMBL8223960 | 0.74 | BCL3 (0.70) | MEN1KMT2ABCL3SMN1; SMN2 | |
| SCHEMBL16995312 | 0.74 | L3MBTL1 (0.54) | L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1845973-B1 | PHARMACEUTICAL COMPOUNDS | ASTEX THERAPEUTICS LTD (GB) | 2015-08-12 | — | — | EP | disclosed |