Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GNAI3 | P08754 | 1/20 | 0.39 |
| ▸ | GNAO1 | P09471 | 1/20 | 0.39 |
| ▸ | GNAI1 | P63096 | 1/20 | 0.39 |
| ▸ | ADH1B | P00325 | 3/20 | 0.33 |
| ▸ | ADH1A | P07327 | 3/20 | 0.33 |
| ▸ | ADH7 | P40394 | 3/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | ADH1C | P00326 | 2/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.31 |
| ▸ | CNR1 | P21554 | 1/20 | 0.31 |
| ▸ | CNR2 | P34972 | 1/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 2/20 | 0.31 |
| ▸ | CARM1 | Q86X55 | 1/20 | 0.30 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.30 |
| ▸ | PRMT8 | Q9NR22 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1307987 | 0.89 | ADH1B (0.38) | GNAI3GNAO1GNAI1ADH1BADH1A | |
| SCHEMBL12465581 | 0.83 | ACE2 (0.48) | KMT2AACE2MEN1CYP2C19CNR1 | |
| SCHEMBL14431493 | 0.83 | — | — | |
| SCHEMBL4166363 | 0.82 | GNAI3 (0.41) | GNAI3GNAO1GNAI1ADH1BADH1A | |
| SCHEMBL1785087 | 0.79 | GNAI3 (0.44) | GNAI3GNAO1GNAI1ADH1BADH1A | |
| SCHEMBL1307631 | 0.79 | CARM1 (0.50) | GNAI3GNAO1GNAI1ADH1BADH1A | |
| SCHEMBL5748707 | 0.79 | — | — | |
| SCHEMBL3947829 | 0.78 | ADH1B (0.50) | GNAI3GNAO1GNAI1ADH1BADH1A | |
| SCHEMBL19981892 | 0.77 | CARM1 (0.48) | GNAI3GNAO1GNAI1KMT2AMEN1 | |
| SCHEMBL21051897 | 0.77 | KMT2A (0.36) | KMT2AMEN1CYP2C19CYP1A2NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2576586-B1 | C-28 AMIDES OF MODIFIED C-3 BETULINIC ACID DERIVATIVES AS HIV MATURATION INHIBITORS | BRISTOL MYERS SQUIBB CO (US) | 2015-08-12 | — | — | EP | disclosed |