Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADH1B | P00325 | 4/20 | 0.34 |
| ▸ | ADH1A | P07327 | 4/20 | 0.34 |
| ▸ | ADH7 | P40394 | 3/20 | 0.34 |
| ▸ | ADH1C | P00326 | 3/20 | 0.33 |
| ▸ | KDM4C | Q9H3R0 | 3/20 | 0.33 |
| ▸ | KDM4A | O75164 | 2/20 | 0.33 |
| ▸ | PHF8 | Q9UPP1 | 1/20 | 0.33 |
| ▸ | KDM2A | Q9Y2K7 | 1/20 | 0.33 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.32 |
| ▸ | GABRP | O00591 | 2/20 | 0.31 |
| ▸ | GABRD | O14764 | 2/20 | 0.31 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.31 |
| ▸ | GABRB1 | P18505 | 2/20 | 0.31 |
| ▸ | GABRG2 | P18507 | 2/20 | 0.31 |
| ▸ | GABRB3 | P28472 | 2/20 | 0.31 |
| ▸ | GABRA5 | P31644 | 2/20 | 0.31 |
| ▸ | GABRA3 | P34903 | 2/20 | 0.31 |
| ▸ | GABRA2 | P47869 | 2/20 | 0.31 |
| ▸ | GABRB2 | P47870 | 2/20 | 0.31 |
| ▸ | GABRA4 | P48169 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16995376 | 0.86 | ADH1B (0.34) | ADH1BADH1AADH7ADH1CADRA1A | |
| SCHEMBL4247084 | 0.82 | GABRP (0.42) | KDM4CKDM4APHF8KDM2AGABRP | |
| SCHEMBL22350659 | 0.79 | ADH1B (0.48) | ADH1BADH1AADH7ADH1CEPHX1 | |
| SCHEMBL24577158 | 0.75 | ADH1B (0.34) | ADH1BADH1AADH7ADH1CEPHX1 | |
| SCHEMBL12269098 | 0.75 | CAMK2A (0.37) | KDM4CKDM4APHF8KDM2AGABRP | |
| SCHEMBL3187223 | 0.75 | FFAR3 (0.44) | KDM4CEPHX2 | |
| SCHEMBL16995352 | 0.75 | ADH1B (0.36) | ADH1BADH1AADH7ADH1CKDM4C | |
| SCHEMBL17232314 | 0.74 | KDM4C (0.32) | KDM4CKDM4APHF8KDM2AGABRP | |
| SCHEMBL23693497 | 0.73 | KDM4C (0.47) | KDM4CKDM4APHF8KDM2AGABRP | |
| SCHEMBL26209746 | 0.72 | TDP1 (0.39) | KDM4CKDM4APHF8KDM2AADRA1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2576586-B1 | C-28 AMIDES OF MODIFIED C-3 BETULINIC ACID DERIVATIVES AS HIV MATURATION INHIBITORS | BRISTOL MYERS SQUIBB CO (US) | 2015-08-12 | — | — | EP | disclosed |