SCHEMBL4247084

SCHEMBL4247084

CC(C)N(CCC(=O)O)CCC(=O)O

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GABRP O00591 2/20 0.42
GABRD O14764 2/20 0.42
GABRA1 P14867 2/20 0.42
GABRB1 P18505 2/20 0.42
GABRG2 P18507 2/20 0.42
GABRB3 P28472 2/20 0.42
GABRA5 P31644 2/20 0.42
GABRA3 P34903 2/20 0.42
GABRA2 P47869 2/20 0.42
GABRB2 P47870 2/20 0.42
GABRA4 P48169 2/20 0.42
GABRE P78334 2/20 0.42
GABRA6 Q16445 2/20 0.42
GABRG1 Q8N1C3 2/20 0.42
GABRG3 Q99928 2/20 0.42
GABRQ Q9UN88 2/20 0.42
CYP1A2 P05177 1/20 0.42
PHF8 Q9UPP1 5/20 0.41
KDM2A Q9Y2K7 5/20 0.41
KDM4C Q9H3R0 2/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12269098 0.91 CAMK2A (0.37) GABRPGABRDGABRA1GABRB1GABRG2
SCHEMBL3187223 0.91 FFAR3 (0.44) KDM4CFFAR3HDAC3HDAC1HDAC2
SCHEMBL23693497 0.89 KDM4C (0.47) GABRPGABRDGABRA1GABRB1GABRG2
SCHEMBL3195705 0.88 ALDH1A1 (0.42) GABRPGABRDGABRA1GABRB1GABRG2
SCHEMBL26209746 0.88 TDP1 (0.39) GABRPGABRDGABRA1GABRB1GABRG2
SCHEMBL11342740 0.87 AKR1B1 (0.46) PHF8KDM4CALDH1A1SLC22A6TSHR
SCHEMBL10246717 0.86 KDM4C (0.44) GABRPGABRDGABRA1GABRB1GABRG2
SCHEMBL11212413 0.86 GABRP (0.41) GABRPGABRDGABRA1GABRB1GABRG2
SCHEMBL20198667 0.86 KDM4C (0.37) GABRPGABRDGABRA1GABRB1GABRG2
SCHEMBL26724520 0.84 LMNA (0.41) GABRPGABRDGABRA1GABRB1GABRG2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 33 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10730892-B2 Homoallylamines as formaldehyde-responsive triggers THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2020-08-04 US disclosed
EP-3109702-B1 RESIN LAMINATE AND RELIEF PRINTING ORIGINAL PLATE TORAY INDUSTRIES (JP) 2020-06-24 EP disclosed
EP-3346333-B1 PHOTOSENSITIVE RESIN PRINTING PLATE PRECURSOR, AND METHOD FOR MANUFACTURING PRINTING PLATE TORAY INDUSTRIES (JP) 2020-03-18 EP disclosed
US-10583679-B2 Photosensitive resin printing plate precursor and method of manufacturing printing plate TORAY INDUSTRIES, INC. (JP) 2020-03-10 US disclosed
EP-2960066-B1 USE OF A RESIN PRINTING PLATE PRECURSOR FOR LASER ENGRAVING AND METHOD OF MANUFACTURING A PRINTING PLATE TORAY INDUSTRIES (JP) 2019-06-12 EP disclosed
US-20190039397-A1 PHOTOSENSITIVE RESIN PRINTING PLATE PRECURSOR AND METHOD OF MANUFACTURING PRINTING PLATE TORAY INDUSTRIES, INC. (JP) 2019-02-07 US disclosed
US-10042257-B2 Resin laminate and relief printing original plate TORAY INDUSTRIES, INC. (JP) 2018-08-07 US disclosed
US-20180215773-A1 HOMOALLYLAMINES AS FORMALDEHYDE-RESPONSIVE TRIGGERS THE REGENTS OF THE UNIVERSITY OF CALIFORNIA 2018-08-02 US disclosed
EP-3346333-A1 PHOTOSENSITIVE RESIN PRINTING PLATE PRECURSOR, AND METHOD FOR MANUFACTURING PRINTING PLATE Toray Industries, Inc. (JP) 2018-07-11 EP disclosed
US-9701667-B2 Coumarin-based fluorogenic agents and uses thereof for specific protein labelling UNIVERSITY OF OTTAWA (CA) 2017-07-11 US disclosed
EP-0201340-B1 TONER COMPOSITION AND METHOD FOR PREPARING THE SAME Kao Corporation (JP) 1992-04-01 EP disclosed
US-4749638-A CARBON BLACK, DISPERSANT, POLYMERIC BINDER OIL PHASE EMULSION POLYMERIZATION KAO CORPORATION (JP) 1988-06-07 US disclosed
EP-0201340-A2 Toner composition and method for preparing the same Kao Corporation (JP) 1986-11-12 EP disclosed
EP-0039226-B1 RESIN COMPOSITION COMPRISING WATER-SOLUBLE POLYAMIDE AND VINYL ALCOHOL-BASED POLYMER UNITIKA LTD. (JP) 1985-10-02 EP disclosed
US-4365041-A LIGHT SENSITIVE, ADHESIVES UNITIKA LTD. (JP) 1982-12-21 US disclosed
EP-0039226-A2 Resin composition comprising water-soluble polyamide and vinyl alcohol-based polymer UNITIKA LTD. (JP) 1981-11-04 EP disclosed
US-4220704-A Water soluble photosensitive resin compositions comprising a polyamide or its salt TOYOBO CO., LTD. (JP) 1980-09-02 US disclosed
US-4187112-A Photosensitive plate containing nitrogen containing condensation type polyesters TOYOBO CO., LTD. (JP) 1980-02-05 US disclosed
US-4145222-A Water soluble photosensitive resin composition comprising a polyamide or its ammonium salt TOYOBO CO., LTD. (JP) 1979-03-20 US disclosed
US-4096123-A COPOLYMER CONTAINING A TERTIARY AMINO GROUP TOYO BOSEKI KABUSHIKI KAISHA (JA) 1978-06-20 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20180215773-A1 HOMOALLYLAMINES AS FORMALDEHYDE-RESPONSIVE TRIGGERS HCAR2, HCAR1, HTR2A GABRP 3386/4885GABRD 2068/4885GABRA1 1593/4885
US-10730892-B2 Homoallylamines as formaldehyde-responsive triggers HCAR2, MTHFD2, AHCY GABRP 4072/4885GABRD 2009/4885GABRA1 2239/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.