SCHEMBL1699565

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL15165216	0.92	CYP3A4 (0.38)	CYP3A4PSIP1PTGDR2
	SCHEMBL1699425	0.90	CYP3A4 (0.44)	CYP3A4PSIP1PTGDR2KCNH2SLCO1B1
	SCHEMBL1699777	0.90	CYP3A4 (0.50)	CYP3A4PSIP1PTGDR2
	SCHEMBL10271610	0.89	CYP3A4 (0.49)	CYP3A4PSIP1PTGDR2
	SCHEMBL1699360	0.89	CYP3A4 (0.43)	CYP3A4PSIP1PTGDR2KCNH2SLCO1B1
	SCHEMBL1699335	0.88	PSIP1 (0.50)	CYP3A4PSIP1PTGDR2
	SCHEMBL1699336	0.87	CYP3A4 (0.44)	CYP3A4PSIP1PTGDR2KCNH2SLCO1B1
	SCHEMBL1699367	0.86	CYP3A4 (0.47)	CYP3A4PSIP1PTGDR2PPARG
	SCHEMBL10271607	0.86	CYP3A4 (0.47)	CYP3A4PSIP1PTGDR2
	SCHEMBL1699418	0.85	PSIP1 (0.44)	CYP3A4PSIP1PTGDR2KCNH2PPARA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.