SCHEMBL1699650

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL1699293	0.90	CYP3A4 (0.37)	CYP3A4ALOX5PTGESMAPTMEN1
	SCHEMBL1699488	0.89	CYP3A4 (0.46)	CYP3A4ABCB1PTGESMAPTPSIP1
	SCHEMBL15171376	0.89	CYP3A4 (0.46)	CYP3A4ABCB1PTGESMAPTPSIP1
	SCHEMBL1699295	0.87	CYP3A4 (0.35)	CYP3A4ALOX5PTGESMAPTMEN1
	SCHEMBL1699420	0.85	MTNR1B (0.38)	CNR2CYP3A4MTNR1BMTNR1AABCB1
	SCHEMBL10271691	0.84	CYP3A4 (0.39)	CYP3A4ALOX5PTGESMAPTMEN1
	SCHEMBL1699377	0.83	PTPN11 (0.37)	MTNR1BMTNR1AMAPTMEN1KMT2A
	SCHEMBL15165159	0.81	TNKS (0.34)	CYP3A4ABCB1MAPTCYP1A2CYP2C19
	SCHEMBL15165318	0.81	TNKS (0.34)	CYP3A4ABCB1MAPTCYP1A2CYP2C19
	SCHEMBL1699594	0.81	PTGDR2 (0.40)	CYP3A4MAPTMEN1KMT2AXBP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.