SCHEMBL1699377

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL1699736	0.85	PTPN11 (0.41)	PTPN11MAPTKDM4EPPARGPPARA
	SCHEMBL1699290	0.84	L3MBTL1 (0.38)	MAPTHPGDKDM4EALDH1A1PPARG
	SCHEMBL1699650	0.83	CNR2 (0.37)	MTNR1AMTNR1BMAPTHPGDALDH1A1
	SCHEMBL1699420	0.81	MTNR1B (0.38)	MTNR1AMTNR1BMAPTHPGDKDM4E
	SCHEMBL1699415	0.78	PTGDR2 (0.41)	PTPN11MAPTHPGDKDM4EALDH1A1
	SCHEMBL1699394	0.77	TOP2A (0.34)	MAPTHPGDKDM4EALDH1A1TP53
	SCHEMBL27903975	0.77	NOD2 (0.37)	MAPTHPGDALDH1A1TP53MDM2
	SCHEMBL1699408	0.74	CYP19A1 (0.42)	PTPN11MAPTHPGDALDH1A1PPARG
	SCHEMBL1699312	0.74	ALOX15 (0.39)	PTPN11ALDH1A1MEN1KMT2AALOX15
	SCHEMBL15171376	0.74	CYP3A4 (0.46)	MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.