SCHEMBL16997267

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL16997255	0.94	L3MBTL1 (0.43)	ALDH1A1RXFP1LMNAKDM4EATM
	SCHEMBL16997280	0.94	L3MBTL1 (0.43)	ALDH1A1RXFP1LMNAKDM4EATM
	SCHEMBL16997308	0.92	RXFP1 (0.37)	ALDH1A1RXFP1LMNAGAAAKR1C4
	SCHEMBL17714816	0.91	PTGER4 (0.38)	ALDH1A1RXFP1LMNAKDM4EATM
	SCHEMBL16997268	0.90	L3MBTL1 (0.44)	ALDH1A1RXFP1LMNAKDM4EATM
	SCHEMBL16997278	0.90	AKR1C4 (0.36)	ALDH1A1RXFP1LMNAKDM4EATM
	SCHEMBL16997286	0.90	ALDH1A1 (0.37)	ALDH1A1RXFP1LMNAKDM4EATM
	SCHEMBL16997287	0.90	ALDH1A1 (0.37)	ALDH1A1RXFP1LMNAKDM4EATM
	SCHEMBL24825990	0.89	KDM4E (0.41)	RXFP1LMNAKDM4EATML3MBTL1
	SCHEMBL24703426	0.88	KDM4E (0.38)	RXFP1LMNAKDM4EATML3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.