SCHEMBL16997286

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL16997287	1.00	ALDH1A1 (0.37)	ALDH1A1RXFP1AKR1C4AKR1C3AKR1C2
	SCHEMBL16997278	0.98	AKR1C4 (0.36)	ALDH1A1RXFP1AKR1C4AKR1C3AKR1C2
	SCHEMBL16997266	0.96	L3MBTL1 (0.38)	ALDH1A1RXFP1AKR1C4AKR1C3AKR1C2
	SCHEMBL16997279	0.95	ALDH1A1 (0.34)	ALDH1A1RXFP1AKR1C4AKR1C3AKR1C2
	SCHEMBL16997270	0.93	RXFP1 (0.35)	ALDH1A1RXFP1LMNAGAAMEN1
	SCHEMBL16997282	0.92	KDM4E (0.36)	RXFP1AKR1C4AKR1C3AKR1C2AKR1C1
	SCHEMBL16997288	0.92	TP53 (0.34)	ALDH1A1RXFP1AKR1C4AKR1C3AKR1C2
	SCHEMBL16997277	0.91	RXFP1 (0.35)	ALDH1A1RXFP1AKR1C4AKR1C3AKR1C2
	SCHEMBL16997267	0.90	ALDH1A1 (0.38)	ALDH1A1RXFP1AKR1C4AKR1C3AKR1C2
	SCHEMBL16997289	0.89	MAPT (0.37)	ALDH1A1RXFP1LMNAMEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.