SCHEMBL16997274

SCHEMBL16997274

Cc1ccc(-c2nc(-c3ccccc3)nc(-c3ccccc3)n2)cc1-c1cccc2c1c1cc(-c3ccccc3)ccc1n2-c1cccc(-c2ccccc2)c1

nearest known ligand 0.37

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PDE10A Q9Y233 1/20 0.33
CYP17A1 P05093 1/20 0.33
CYP1A2 P05177 1/20 0.33
PTGER1 P34995 1/20 0.33
LMNA P02545 2/20 0.33
MEN1 O00255 1/20 0.33
NPC1 O15118 1/20 0.33
RAB9A P51151 1/20 0.33
KMT2A Q03164 1/20 0.33
AVPR1A P37288 1/20 0.33
MTOR P42345 1/20 0.33
BLK P51451 1/20 0.33
BMX P51813 1/20 0.33
JAK3 P52333 1/20 0.33
BTK Q06187 1/20 0.33
L3MBTL1 Q9Y468 1/20 0.32
TSHR P16473 2/20 0.32
PTGER4 P35408 1/20 0.32
RXFP1 Q9HBX9 1/20 0.31
HTR1A P08908 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16997276 0.97 AVPR1A (0.36) CYP17A1CYP1A2PTGER1LMNAMEN1
SCHEMBL16997275 0.95 RXRA (0.34) CYP17A1CYP1A2LMNAMEN1NPC1
SCHEMBL16997277 0.94 RXFP1 (0.35) PDE10ALMNAMEN1NPC1RAB9A
SCHEMBL16997282 0.91 KDM4E (0.36) PDE10ACYP17A1CYP1A2PTGER1LMNA
SCHEMBL16997266 0.91 L3MBTL1 (0.38) PDE10ACYP17A1CYP1A2LMNAMEN1
SCHEMBL26385557 0.89 PTGER4 (0.37) PDE10ACYP17A1CYP1A2PTGER1AVPR1A
SCHEMBL26385573 0.88 PTGER4 (0.38) PDE10ACYP17A1CYP1A2MEN1NPC1
SCHEMBL16997270 0.88 RXFP1 (0.35) PDE10ACYP17A1CYP1A2LMNAMEN1
SCHEMBL19009284 0.88 PDE10A (0.36) PDE10AMEN1KMT2AJAK3L3MBTL1
SCHEMBL19009242 0.88 PDE10A (0.36) PDE10AMEN1KMT2AJAK3L3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11706983-B2 Organic light-emitting device SAMSUNG ELECTRONICS CO., LTD. (KR) 2023-07-18 US disclosed
US-11706983-B2 Organic light-emitting device SAMSUNG ELECTRONICS CO., LTD. (KR) 2023-07-18 US disclosed
US-20200295272-A1 ORGANIC LIGHT-EMITTING DEVICE SAMSUNG ELECTRONICS CO., LTD. (KR) 2020-09-17 US disclosed
US-10741772-B2 Organic light-emitting device SAMSUNG ELECTRONICS CO., LTD. (KR) 2020-08-11 US disclosed
US-9911925-B2 Carbazole-based compound and organic light-emitting device including the same SAMSUNG ELECTRONICS CO., LTD. (KR) 2018-03-06 US disclosed
US-9911925-B2 Carbazole-based compound and organic light-emitting device including the same SAMSUNG ELECTRONICS CO., LTD. (KR) 2018-03-06 US disclosed
EP-2991128-B1 ORGANIC LIGHT-EMITTING DEVICE SAMSUNG ELECTRONICS CO LTD (KR) 2017-04-12 EP disclosed
US-20160072078-A1 ORGANIC LIGHT-EMITTING DEVICE SAMSUNG ELECTRONICS CO., LTD. (KR) 2016-03-10 US disclosed
US-20160072078-A1 ORGANIC LIGHT-EMITTING DEVICE SAMSUNG ELECTRONICS CO., LTD. (KR) 2016-03-10 US disclosed
EP-2991128-A1 ORGANIC LIGHT-EMITTING DEVICE Samsung Electronics Co., Ltd. (KR) 2016-03-02 EP disclosed
US-20150228908-A1 CARBAZOLE-BASED COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE SAME SAMSUNG SDI CO., LTD. (KR) 2015-08-13 US disclosed
US-20150228908-A1 CARBAZOLE-BASED COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE SAME SAMSUNG SDI CO., LTD. (KR) 2015-08-13 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20150228908-A1 CARBAZOLE-BASED COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE SAME CYP1B1, CYP1A1, CRY1 PDE10A 3614/4885CYP17A1 1664/4885CYP1A2 8/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.