SCHEMBL16997275

SCHEMBL16997275

Cc1ccc(-c2nc(-c3ccccc3)nc(-c3ccccc3)n2)cc1-c1cccc2c1c1cc(-c3ccccc3)ccc1n2-c1ccc(-c2ccccc2)cc1

nearest known ligand 0.37

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
RXRA P19793 1/20 0.34
AVPR1A P37288 1/20 0.33
MEN1 O00255 1/20 0.33
NPC1 O15118 1/20 0.33
LMNA P02545 1/20 0.33
RAB9A P51151 1/20 0.33
KMT2A Q03164 1/20 0.33
MTOR P42345 1/20 0.33
BLK P51451 1/20 0.33
BMX P51813 1/20 0.33
JAK3 P52333 1/20 0.33
BTK Q06187 1/20 0.33
NR3C1 P04150 2/20 0.33
PGR P06401 1/20 0.33
L3MBTL1 Q9Y468 1/20 0.33
ALK Q9UM73 2/20 0.32
PTGER4 P35408 1/20 0.32
RXFP1 Q9HBX9 1/20 0.32
CYP17A1 P05093 1/20 0.32
CYP1A2 P05177 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16997276 0.98 AVPR1A (0.36) RXRAAVPR1AMEN1NPC1LMNA
SCHEMBL16997277 0.95 RXFP1 (0.35) AVPR1AMEN1NPC1LMNARAB9A
SCHEMBL16997274 0.95 PDE10A (0.33) AVPR1AMEN1NPC1LMNARAB9A
SCHEMBL16997282 0.92 KDM4E (0.36) MEN1NPC1LMNARAB9AKMT2A
SCHEMBL16997266 0.92 L3MBTL1 (0.38) RXRAAVPR1AMEN1NPC1LMNA
SCHEMBL16997278 0.90 AKR1C4 (0.36) MEN1LMNAKMT2AL3MBTL1RXFP1
SCHEMBL16997270 0.89 RXFP1 (0.35) RXRAMEN1NPC1LMNARAB9A
SCHEMBL22058820 0.88 ATM (0.36) AVPR1AMEN1NPC1LMNARAB9A
SCHEMBL16997286 0.88 ALDH1A1 (0.37) MEN1LMNAKMT2AL3MBTL1PTGER4
SCHEMBL16997287 0.88 ALDH1A1 (0.37) MEN1LMNAKMT2AL3MBTL1PTGER4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11706983-B2 Organic light-emitting device SAMSUNG ELECTRONICS CO., LTD. (KR) 2023-07-18 US disclosed
US-11706983-B2 Organic light-emitting device SAMSUNG ELECTRONICS CO., LTD. (KR) 2023-07-18 US disclosed
US-20200295272-A1 ORGANIC LIGHT-EMITTING DEVICE SAMSUNG ELECTRONICS CO., LTD. (KR) 2020-09-17 US disclosed
US-10741772-B2 Organic light-emitting device SAMSUNG ELECTRONICS CO., LTD. (KR) 2020-08-11 US disclosed
US-9911925-B2 Carbazole-based compound and organic light-emitting device including the same SAMSUNG ELECTRONICS CO., LTD. (KR) 2018-03-06 US disclosed
US-9911925-B2 Carbazole-based compound and organic light-emitting device including the same SAMSUNG ELECTRONICS CO., LTD. (KR) 2018-03-06 US disclosed
EP-2991128-B1 ORGANIC LIGHT-EMITTING DEVICE SAMSUNG ELECTRONICS CO LTD (KR) 2017-04-12 EP disclosed
US-20160072078-A1 ORGANIC LIGHT-EMITTING DEVICE SAMSUNG ELECTRONICS CO., LTD. (KR) 2016-03-10 US disclosed
US-20160072078-A1 ORGANIC LIGHT-EMITTING DEVICE SAMSUNG ELECTRONICS CO., LTD. (KR) 2016-03-10 US disclosed
EP-2991128-A1 ORGANIC LIGHT-EMITTING DEVICE Samsung Electronics Co., Ltd. (KR) 2016-03-02 EP disclosed
US-20150228908-A1 CARBAZOLE-BASED COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE SAME SAMSUNG SDI CO., LTD. (KR) 2015-08-13 US disclosed
US-20150228908-A1 CARBAZOLE-BASED COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE SAME SAMSUNG SDI CO., LTD. (KR) 2015-08-13 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20150228908-A1 CARBAZOLE-BASED COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE SAME CYP1B1, CYP1A1, CRY1 RXRA 832/4885AVPR1A 2930/4885MEN1 1330/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.