Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX15 | P16050 | 1/20 | 0.37 |
| ▸ | CA12 | O43570 | 2/20 | 0.33 |
| ▸ | CA2 | P00918 | 2/20 | 0.33 |
| ▸ | CA9 | Q16790 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | ACHE | P22303 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | CA1 | P00915 | 1/20 | 0.30 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.30 |
| ▸ | KDM5A | P29375 | 1/20 | 0.30 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1699822 | 0.83 | CA1 (0.30) | CA1 | |
| SCHEMBL27909102 | 0.71 | ALOX15 (0.40) | ALOX15ALDH1A1LMNAHSD17B10 | |
| SCHEMBL2127597 | 0.70 | — | — | |
| SCHEMBL28308223 | 0.70 | — | — | |
| SCHEMBL11506574 | 0.70 | ADRB2 (0.35) | ALDH1A1TSHR | |
| SCHEMBL9295293 | 0.70 | DNM1 (0.44) | CA12CA2CA9ALDH1A1LMNA | |
| SCHEMBL27519289 | 0.69 | FFAR3 (0.38) | ALOX15ALDH1A1LMNAHSD17B10TSHR | |
| Butane SCHEMBL9391716 | 0.68 | ACHE (0.58) | ALOX15ALDH1A1LMNAHSD17B10ACHE | |
| Butane SCHEMBL1162354 | 0.68 | — | — | |
| SCHEMBL8924718 | 0.67 | MAPT (0.38) | ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011005980-A1 | NOVEL HETEROBIFUNCTIONAL POLYETHYLENE GLYCOL REAGENTS, THEIR PREPARATION AND USES THEREOF | INTRADIGM CORPORATION (US) | 2011-01-13 | — | — | WO | disclosed |