Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TPSAB1 | Q15661 | 7/20 | 0.45 |
| ▸ | TPSD1 | Q9BZJ3 | 7/20 | 0.45 |
| ▸ | TPSG1 | Q9NRR2 | 7/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.42 |
| ▸ | GRM3 | Q14832 | 1/20 | 0.42 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.42 |
| ▸ | HTR3B | O95264 | 1/20 | 0.42 |
| ▸ | HTR3A | P46098 | 1/20 | 0.42 |
| ▸ | HTR3D | Q70Z44 | 1/20 | 0.42 |
| ▸ | HTR3C | Q8WXA8 | 1/20 | 0.42 |
| ▸ | TAAR1 | Q96RJ0 | 5/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.40 |
| ▸ | GLA | P06280 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16997618 | 0.80 | TPSAB1 (0.44) | TPSAB1TPSD1TPSG1KDM4ETAAR1 | |
| SCHEMBL16997623 | 0.79 | TPSAB1 (0.41) | TPSAB1TPSD1TPSG1KDM4ETAAR1 | |
| SCHEMBL16997584 | 0.79 | CCR5 (0.40) | TPSAB1TPSD1TPSG1TAAR1KMT2A | |
| SCHEMBL27045041 | 0.79 | TPSAB1 (0.41) | TPSAB1TPSD1TPSG1KDM4ETAAR1 | |
| SCHEMBL27046678 | 0.75 | PNMT (0.45) | KDM4EGRM2GRM3HTR3EHTR3B | |
| SCHEMBL24092116 | 0.74 | F11 (0.43) | TPSAB1TPSD1TPSG1GRM2GRM3 | |
| SCHEMBL17002084 | 0.74 | F11 (0.43) | TPSAB1TPSD1TPSG1GRM2GRM3 | |
| SCHEMBL16997578 | 0.74 | F11 (0.43) | TPSAB1TPSD1TPSG1GRM2GRM3 | |
| SCHEMBL27047238 | 0.74 | F11 (0.43) | TPSAB1TPSD1TPSG1GRM2GRM3 | |
| SCHEMBL16998931 | 0.73 | F11 (0.44) | TPSAB1TPSD1TPSG1GRM2GRM3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015120062-A2 | THERAPEUTIC COMPOUNDS AND COMPOSITIONS | eXIthera Pharmaceuticals Inc. (US) | 2015-08-13 | — | — | WO | disclosed |