Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 5/20 | 0.81 |
| ▸ | EBP | Q15125 | 2/20 | 0.81 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.81 |
| ▸ | EBPL | Q9BY08 | 1/20 | 0.74 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.59 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| [11C]Sa4503 SCHEMBL29358558 | 0.90 | SIGMAR1 (1.00) | SIGMAR1EBPTMEM97EBPLABCB1 | |
| [11C]Sa4503 SCHEMBL968642 | 0.90 | SIGMAR1 (1.00) | SIGMAR1EBPTMEM97EBPLABCB1 | |
| [11C]Sa4503 SCHEMBL29358694 | 0.88 | SIGMAR1 (0.97) | SIGMAR1EBPTMEM97EBPLABCB1 | |
| Hydrochloric Acid SCHEMBL8088187 | 0.88 | SIGMAR1 (0.97) | SIGMAR1EBPTMEM97EBPLABCB1 | |
| [11C]Sa4503 SCHEMBL1299046 | 0.88 | SIGMAR1 (0.97) | SIGMAR1EBPTMEM97EBPLABCB1 | |
| SCHEMBL8083210 | 0.87 | SIGMAR1 (0.95) | SIGMAR1EBPTMEM97EBPLABCB1 | |
| SCHEMBL1299348 | 0.86 | SIGMAR1 (0.79) | SIGMAR1EBPTMEM97EBPL | |
| SCHEMBL8086559 | 0.86 | SIGMAR1 (0.92) | SIGMAR1EBPTMEM97EBPLABCB1 | |
| Hydrochloric Acid SCHEMBL8075024 | 0.85 | SIGMAR1 (0.92) | SIGMAR1EBPTMEM97EBPLABCB1 | |
| Hydrochloric Acid SCHEMBL1298925 | 0.85 | SIGMAR1 (0.77) | SIGMAR1EBPTMEM97EBPL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015118365-A1 | NOVEL USE OF SIGMA-1 RECEPTOR AGONIST COMPOUNDS | MTA TÁMOGATOTT KUTATÓCSOPORTOK IRODÁJA (HU) | 2015-08-13 | — | — | WO | disclosed |