Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | NPC1 | O15118 | 2/20 | 0.45 |
| ▸ | RAB9A | P51151 | 2/20 | 0.45 |
| ▸ | PHGDH | O43175 | 5/20 | 0.45 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.42 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.42 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.41 |
| ▸ | HTT | P42858 | 2/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.40 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.40 |
| ▸ | RELA | Q04206 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 3/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | STAT3 | P40763 | 1/20 | 0.40 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.40 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17000511 | 0.80 | MAPT (0.52) | MAPTMEN1KMT2ANPC1RAB9A | |
| SCHEMBL16964049 | 0.78 | MAPT (0.54) | MAPTMEN1KMT2ANPC1RAB9A | |
| SCHEMBL17000548 | 0.74 | MAPT (0.56) | MAPTMEN1KMT2ANPC1RAB9A | |
| SCHEMBL16964168 | 0.71 | MAPT (0.51) | MAPTMEN1KMT2ANPC1RAB9A | |
| SCHEMBL16991074 | 0.69 | MAPT (0.54) | MAPTMEN1KMT2ANPC1RAB9A | |
| SCHEMBL16964226 | 0.68 | ALDH1A1 (0.57) | MAPTMEN1KMT2ANPC1RAB9A | |
| SCHEMBL16964173 | 0.67 | MAPT (0.51) | MAPTMEN1KMT2ANPC1RAB9A | |
| SCHEMBL16964202 | 0.66 | MAPT (0.53) | MAPTMEN1KMT2ANPC1RAB9A | |
| SCHEMBL18359009 | 0.66 | POLB (0.47) | MEN1KMT2ANPC1RAB9APHGDH | |
| SCHEMBL19976508 | 0.66 | MAPT (0.64) | MAPTMEN1KMT2ANPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9920042-B2 | Compounds for use in the treatment of mycobacterial infections | UNIVERSITE DE DROIT ET DE LA SANTE DE LILLE 2 (FR) | 2018-03-20 | — | — | US | disclosed |