Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.40 |
| ▸ | HPGD | P15428 | 4/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.40 |
| ▸ | MEN1 | O00255 | 3/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | PDE4A | P27815 | 1/20 | 0.40 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.40 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.40 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 4/20 | 0.39 |
| ▸ | CA2 | P00918 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | RECQL | P46063 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 2/20 | 0.37 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18268205 | 0.91 | ALDH1A1 (0.47) | ALDH1A1KDM4EHPGDTP53MAPK1 | |
| SCHEMBL18268180 | 0.83 | CA2 (0.44) | ALDH1A1KDM4EHPGDMAPK1MEN1 | |
| SCHEMBL17001453 | 0.81 | KDM4E (0.42) | ALDH1A1KDM4EHPGDMAPK1MEN1 | |
| SCHEMBL17001475 | 0.73 | ALDH1A1 (0.44) | ALDH1A1KDM4EHPGDTP53MAPK1 | |
| SCHEMBL18270510 | 0.72 | KDM4E (0.43) | ALDH1A1KDM4EHPGDMAPK1MEN1 | |
| SCHEMBL18268181 | 0.72 | LMNA (0.38) | ALDH1A1KDM4EHPGDTP53MEN1 | |
| SCHEMBL17001476 | 0.72 | MAPT (0.39) | ALDH1A1KDM4EMAPK1MEN1KMT2A | |
| SCHEMBL18270539 | 0.71 | LMNA (0.42) | ALDH1A1KDM4EHPGDTP53MEN1 | |
| SCHEMBL18270538 | 0.71 | LMNA (0.42) | ALDH1A1KDM4EHPGDTP53MEN1 | |
| SCHEMBL18268186 | 0.70 | KDM4E (0.48) | ALDH1A1KDM4EHPGDMAPK1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015120059-A1 | INHIBITORS OF PAXILLIN FUNCTION AND RELATED COMPOSITIONS AND METHODS | YATES CHARLES RYAN (US) | 2015-08-13 | — | — | WO | disclosed |