Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCRTR1 | O43613 | 1/20 | 0.34 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.34 |
| ▸ | LOX | P28300 | 1/20 | 0.31 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.31 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.30 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17004185 | 0.79 | HCRTR1 (0.39) | HCRTR1HCRTR2 | |
| SCHEMBL17004198 | 0.78 | FURIN (0.40) | HCRTR1HCRTR2 | |
| SCHEMBL17004242 | 0.75 | CHRM2 (0.54) | CHRM2CHRM1 | |
| SCHEMBL17004243 | 0.75 | S1PR4 (0.33) | HCRTR1HCRTR2 | |
| SCHEMBL17004311 | 0.74 | TRPC3 (0.35) | CHRM2CHRM1 | |
| SCHEMBL17004248 | 0.74 | HMOX1 (0.33) | — | |
| SCHEMBL17004273 | 0.73 | ADRA2A (0.35) | — | |
| SCHEMBL17004217 | 0.73 | NPC1 (0.33) | — | |
| SCHEMBL17004329 | 0.72 | LNPEP (0.35) | LOXLOXL2 | |
| SCHEMBL17004214 | 0.70 | HCRTR2 (0.39) | HCRTR1HCRTR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2099795-B1 | AZAADAMANTANE DERIVATIVES AND THEIR USES AS NICOTINIC ACETYLCHOLINE RECEPTORS LIGANDS | ABBVIE BAHAMAS LTD (BS) | 2015-08-19 | — | — | EP | disclosed |