Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.59 |
| ▸ | ACHE | P22303 | 3/20 | 0.59 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.53 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.53 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.46 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.40 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.40 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.40 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.40 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | TYK2 | P29597 | 1/20 | 0.39 |
| ▸ | CA1 | P00915 | 1/20 | 0.39 |
| ▸ | CA2 | P00918 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| O-Xylene SCHEMBL3497383 | 1.00 | TSHR (0.59) | TSHRACHENAPRTTDP1NOTUM | |
| O-Xylene SCHEMBL29229407 | 0.97 | TSHR (0.56) | TSHRACHENAPRTTDP1NOTUM | |
| O-Xylene SCHEMBL1486308 | 0.97 | TSHR (0.56) | TSHRACHENAPRTTDP1NOTUM | |
| O-Xylene SCHEMBL18591322 | 0.88 | ACHE (0.67) | TSHRACHETDP1NOTUMADRA2C | |
| O-Xylene SCHEMBL27528375 | 0.84 | TSHR (0.58) | TSHRACHENAPRTTDP1ADRA2C | |
| O-Tolylamine SCHEMBL28329117 | 0.83 | CYP3A4 (0.65) | TSHRACHENAPRTTDP1NOTUM | |
| Toluene SCHEMBL434901 | 0.82 | ACHE (0.65) | TSHRACHENAPRTTDP1NOTUM | |
| O-Xylene SCHEMBL36981 | 0.82 | ACHE (0.59) | TSHRACHETDP1ADRA2CCYP2A6 | |
| Pyridine SCHEMBL27742398 | 0.81 | TSHR (0.45) | TSHRNAPRTTDP1ADRA2CLMNA | |
| O-Xylene SCHEMBL17318270 | 0.80 | TSHR (0.91) | TSHRACHETDP1LMNAALOX12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2582741-B1 | BORONATED POLYMERS | UNIV TWENTE (NL) | 2016-07-27 | — | — | EP | disclosed |
| US-20130157926-A1 | BORONATED POLYMERS | UNIVERSITEIT TWENTE (NL) | 2013-06-20 | — | — | US | disclosed |
| EP-2582741-A2 | BORONATED POLYMERS | Universiteit Twente (NL) | 2013-04-24 | — | — | EP | disclosed |
| WO-2011159161-A2 | BORONATED POLYMERS | UNIVERSITEIT TWENTE (NL) | 2011-12-22 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130157926-A1 | BORONATED POLYMERS | PHB1, ABCB11, PHB2 | TSHR 2215/4885ACHE 4227/4885NAPRT 2212/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.