Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.46 |
| ▸ | HPGD | P15428 | 3/20 | 0.45 |
| ▸ | RAB9A | P51151 | 3/20 | 0.45 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | POLB | P06746 | 2/20 | 0.42 |
| ▸ | THRB | P10828 | 1/20 | 0.42 |
| ▸ | APEX1 | P27695 | 1/20 | 0.42 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.42 |
| ▸ | RECQL | P46063 | 1/20 | 0.42 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.42 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.42 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL45228 | 0.88 | LMNA (0.50) | LMNAHPGDRAB9ATAAR1ALDH1A1 | |
| SCHEMBL9825918 | 0.86 | LMNA (0.49) | LMNAHPGDRAB9ATAAR1ALDH1A1 | |
| Methane SCHEMBL11161392 | 0.86 | LMNA (0.49) | LMNAHPGDRAB9ATAAR1ALDH1A1 | |
| Ammonia Solution, Strong SCHEMBL27757668 | 0.86 | LMNA (0.49) | LMNAHPGDRAB9ATAAR1ALDH1A1 | |
| SCHEMBL28547424 | 0.84 | CALM1 (0.50) | LMNAHPGDRAB9ATAAR1ALDH1A1 | |
| Methyl Alcohol SCHEMBL5311361 | 0.82 | LMNA (0.50) | LMNAHPGDRAB9ATAAR1ALDH1A1 | |
| Piperazine SCHEMBL28202608 | 0.78 | LMNA (0.42) | LMNAHPGDRAB9ATAAR1ALDH1A1 | |
| Formic Acid Methyl Ester SCHEMBL28451641 | 0.77 | LMNA (0.43) | LMNAHPGDRAB9AALDH1A1POLB | |
| Acrylic Acid SCHEMBL28989981 | 0.77 | LMNA (0.50) | LMNAHPGDRAB9AALDH1A1POLB | |
| SCHEMBL10629184 | 0.77 | CYP17A1 (0.44) | LMNAHPGDRAB9ATAAR1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3288585-A2 | NOVEL COMPOSITIONS AND METHODS FOR IMMUNOTHERAPIES COMPRISING SMALL MOLECULE INTEGRIN RECEPTOR-LIGAND AGONIST ADJUVANTS | 7 HILLS INTERESTS, LLC (US) | 2018-03-07 | — | — | EP | disclosed |
| EP-3104867-A1 | COMPOSITIONS AND METHODS TO IMPROVE THE HOMING AND GRAFTING OF HEMATOPOETIC STEM CELLS | 7 HILLS INTERESTS, LLC (US) | 2016-12-21 | — | — | EP | disclosed |
| WO-2016176400-A2 | NOVEL COMPOSITIONS AND METHODS FOR IMMUNOTHERAPIES COMPRISING SMALL MOLECULE INTEGRIN RECEPTOR-LIGAND AGONIST ADJUVANTS | 7 HILLS INTERESTS LLC (US) | 2016-11-03 | — | — | WO | disclosed |
| WO-2015123447-A1 | COMPOSITIONS AND METHODS TO IMPROVE THE HOMING AND GRAFTING OF HEMATOPOETIC STEM CELLS | 7 HILLS PHARMA, LLC (US) | 2015-08-20 | — | — | WO | disclosed |