SCHEMBL45228

SCHEMBL45228

c1ccc(Cc2cccs2)cc1

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 3/20 0.50
CALM1 P0DP23 1/20 0.50
HPGD P15428 3/20 0.49
RAB9A P51151 2/20 0.49
TAAR1 Q96RJ0 1/20 0.46
CYP2C19 P33261 1/20 0.45
SMN1; SMN2 Q16637 2/20 0.45
NPC1 O15118 1/20 0.45
TSHR P16473 1/20 0.44
CYP2C9 P11712 1/20 0.44
ALDH1A1 P00352 1/20 0.44
POLB P06746 1/20 0.44
THRB P10828 1/20 0.44
APEX1 P27695 1/20 0.44
APOBEC3A P31941 1/20 0.44
RECQL P46063 1/20 0.44
MCL1 Q07820 1/20 0.44
ESR2 Q92731 1/20 0.44
APOBEC3G Q9HC16 1/20 0.44
TDP1 Q9NUW8 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Ammonia Solution, Strong SCHEMBL27757668 0.98 LMNA (0.49) LMNACALM1HPGDRAB9ATAAR1
SCHEMBL9825918 0.98 LMNA (0.49) LMNACALM1HPGDRAB9ATAAR1
Methane SCHEMBL11161392 0.98 LMNA (0.49) LMNACALM1HPGDRAB9ATAAR1
SCHEMBL28547424 0.95 CALM1 (0.50) LMNACALM1HPGDRAB9ATAAR1
Methyl Alcohol SCHEMBL5311361 0.94 LMNA (0.50) LMNACALM1HPGDRAB9ATAAR1
Piperazine SCHEMBL28202608 0.88 LMNA (0.42) LMNACALM1HPGDRAB9ATAAR1
SCHEMBL17009265 0.88 LMNA (0.46) LMNACALM1HPGDRAB9ATAAR1
SCHEMBL10629184 0.87 CYP17A1 (0.44) LMNAHPGDRAB9ATAAR1CYP2C19
Phenol SCHEMBL5653416 0.84 L3MBTL1 (0.50) LMNAHPGDRAB9ACYP2C19CYP2C9
Formic Acid Methyl Ester SCHEMBL28451641 0.84 LMNA (0.43) LMNAHPGDRAB9ACYP2C19SMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 5541 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4642314-A2 APTAMER PROTECTIVE MATERIAL AND BIOSENSOR DexCom, Inc. (US) 2025-11-05 EP claimed
CN-120058585-A Dimercapto conjugate of active allyl alcohol acetate, and preparation method and application thereof 南京工业大学 2025-05-30 CN claimed
CN-119861532-A Gold nanocluster photoresist added with coinitiators and method 浙江大学 2025-04-22 CN claimed
US-12270631-B2 Personal security device MANUFACTURING COST CALCULATION (MCCAB) AKTIEBOLAG (SE) 2025-04-08 US claimed
CN-119767902-A Color conversion film, light-emitting device and preparation method of light-emitting device 广东聚华印刷显示技术有限公司 2025-04-04 CN claimed
CN-119707607-A Process for cyanation of carbon-sulfur bonds in sulfur-containing compounds 中国科学院大连化学物理研究所 2025-03-28 CN claimed
US-12240919-B2 Method for supporting thiol group-including compound KANEKA CORPORATION (JP) 2025-03-04 US claimed
CN-119465190-A Selective cleavage method of small molecule mercaptan-mediated lignin beta-O-4 connection 烟台先进材料与绿色制造山东省实验室 2025-02-18 CN claimed
US-20250025076-A1 APTAMER PROTECTIVE MATERIAL AND BIOSENSOR DEXCOM, INC. (US) 2025-01-23 US claimed
CN-119233943-A Surface-treated boron nitride nanotubes and surface treatment method for boron nitride nanotubes 耐尔泰科株式会社 2024-12-31 CN claimed
EP-0133649-B1 IMPROVING THE LIFE OF A CATALYST USED TO PROCESS HYDROCARBON CONTAINING FEED STREAMS PHILLIPS PETROLEUM COMPANY (US) 1988-05-11 EP claimed
CN-86102736-A The preparation method and the application thereof of 6-(1-acyl group-1-methylol) penicillanic acid derivative 1986-10-15 CN claimed
CN-85108458-A New 9-chloro-1,5-benzo thiophene is at product derivative and preparation method thereof 1986-07-30 CN claimed
US-4564441-A Hydrofining process for hydrocarbon-containing feed streams PHILLIPS PETROLEUM COMPANY (US) 1986-01-14 US claimed
EP-0136469-A1 Hydrofining process for hydrocarbon-containing feed streams PHILLIPS PETROLEUM COMPANY (US) 1985-04-10 EP claimed
EP-0133649-A1 Improving the life of a catalyst used to process hydrocarbon containing feed streams PHILLIPS PETROLEUM COMPANY (US) 1985-03-06 EP claimed
EP-0040955-B1 3,4-DIHYDROXYPHENYLTETRAHYDROTHIENOPYRIDINES SMITHKLINE BECKMAN CORPORATION (US) 1984-06-27 EP claimed
EP-0078668-A1 Preparation of aminocyclopentanealkenoic acids GLAXO GROUP LIMITED (GB) 1983-05-11 EP claimed
US-4369322-A WITH CYANOGEN CHLORIDE DEGUSSA AG (DE) 1983-01-18 US claimed
US-3971820-A TETRAMIZATION OF HALOGEN CYANIDE, BASIC CATALYST NIPPON SODA COMPANY LIMITED (JA) 1976-07-27 US claimed