Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.49 |
| ▸ | CALM1 | P0DP23 | 1/20 | 0.48 |
| ▸ | HPGD | P15428 | 3/20 | 0.47 |
| ▸ | RAB9A | P51151 | 2/20 | 0.47 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | THRB | P10828 | 1/20 | 0.43 |
| ▸ | APEX1 | P27695 | 1/20 | 0.43 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.43 |
| ▸ | RECQL | P46063 | 1/20 | 0.43 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.43 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.43 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL45228 | 0.98 | LMNA (0.50) | LMNACALM1HPGDRAB9ATAAR1 | |
| Ammonia Solution, Strong SCHEMBL27757668 | 0.95 | LMNA (0.49) | LMNACALM1HPGDRAB9ATAAR1 | |
| Methane SCHEMBL11161392 | 0.95 | LMNA (0.49) | LMNACALM1HPGDRAB9ATAAR1 | |
| SCHEMBL28547424 | 0.93 | CALM1 (0.50) | LMNACALM1HPGDRAB9ATAAR1 | |
| Methyl Alcohol SCHEMBL5311361 | 0.91 | LMNA (0.50) | LMNACALM1HPGDRAB9ATAAR1 | |
| Piperazine SCHEMBL28202608 | 0.86 | LMNA (0.42) | LMNACALM1HPGDRAB9ATAAR1 | |
| SCHEMBL17009265 | 0.86 | LMNA (0.46) | LMNACALM1HPGDRAB9ATAAR1 | |
| SCHEMBL10629184 | 0.85 | CYP17A1 (0.44) | LMNAHPGDRAB9ATAAR1CYP2C19 | |
| Phenol SCHEMBL5653416 | 0.82 | L3MBTL1 (0.50) | LMNAHPGDRAB9ACYP2C19CYP2C9 | |
| Acrylic Acid SCHEMBL28989981 | 0.82 | LMNA (0.50) | LMNAHPGDRAB9ACYP2C19SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0165753-B1 | HERBICIDAL THIOPHENESULFONAMIDES AND PYRIDINESULFONAMIDES | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1991-12-11 | — | — | EP | disclosed |
| US-4784684-A | Herbicidal pyridinesulfonamides | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1988-11-15 | — | — | US | disclosed |
| US-4668279-A | PLANT GROWTH REGULATORS | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1987-05-26 | — | — | US | disclosed |
| EP-0165753-A2 | Herbicidal thiophenesulfonamides and pyridinesulfonamides | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1985-12-27 | — | — | EP | disclosed |