Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | XDH | P47989 | 17/20 | 0.57 |
| ▸ | SLC22A12 | Q96S37 | 11/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.51 |
| ▸ | USP2 | O75604 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.51 |
| ▸ | LMNA | P02545 | 1/20 | 0.51 |
| ▸ | POLB | P06746 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 1/20 | 0.51 |
| ▸ | HPGD | P15428 | 1/20 | 0.51 |
| ▸ | CASP1 | P29466 | 1/20 | 0.51 |
| ▸ | BRCA1 | P38398 | 1/20 | 0.51 |
| ▸ | HTT | P42858 | 1/20 | 0.51 |
| ▸ | CASP7 | P55210 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.51 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.51 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17010221 | 0.82 | XDH (0.67) | XDHSLC22A12KDM4EMEN1USP2 | |
| SCHEMBL17010326 | 0.81 | XDH (0.66) | XDHSLC22A12KDM4EMEN1USP2 | |
| SCHEMBL17010257 | 0.81 | XDH (0.66) | XDHSLC22A12KDM4EMEN1USP2 | |
| SCHEMBL10334083 | 0.75 | CFD (0.63) | KDM4EMEN1ALDH1A1LMNAHPGD | |
| SCHEMBL17010317 | 0.74 | XDH (0.70) | XDHSLC22A12KDM4EMEN1USP2 | |
| SCHEMBL17010244 | 0.74 | XDH (0.77) | XDHSLC22A12KDM4EMEN1USP2 | |
| SCHEMBL20179459 | 0.73 | XDH (1.00) | XDHSLC22A12KDM4EMEN1USP2 | |
| SCHEMBL16708623 | 0.73 | XDH (0.78) | XDHSLC22A12KDM4EMEN1USP2 | |
| SCHEMBL16700088 | 0.72 | XDH (1.00) | XDHSLC22A12KDM4EMEN1USP2 | |
| SCHEMBL10926831 | 0.72 | SLC22A12 (1.00) | XDHSLC22A12KDM4EMEN1USP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10093631-B2 | Bifunctional compounds and use for reducing uric acid levels | ACQUIST LLC (US) | 2018-10-09 | — | — | US | disclosed |
| US-20170197923-A1 | Bifunctional Compounds and Use for Reducing Uric Acid Levels | ACQUIST LLC | 2017-07-13 | — | — | US | disclosed |
| EP-3104861-A1 | BIFUNCTIONAL COMPOUNDS AND USE FOR REDUCING URIC ACID LEVELS | Warrell, Raymond P., Jr. (US) | 2016-12-21 | — | — | EP | disclosed |
| WO-2015123003-A1 | BIFUNCTIONAL COMPOUNDS AND USE FOR REDUCING URIC ACID LEVELS | WARRELL RAYMOND P (US) | 2015-08-20 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170197923-A1 | Bifunctional Compounds and Use for Reducing Uric Acid Levels | XDH, OAT, ATIC | XDH 1/4885SLC22A12 264/4885KDM4E 4691/4885 |
| US-10093631-B2 | Bifunctional compounds and use for reducing uric acid levels | XDH, OAT, ATIC | XDH 1/4885SLC22A12 264/4885KDM4E 4691/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.