SCHEMBL17010758

SCHEMBL17010758

O=C(OCc1ccco1)c1ccccc1O

nearest known ligand 0.65

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 5/20 0.65
L3MBTL1 Q9Y468 4/20 0.65
CTDSP1 Q9GZU7 1/20 0.65
ALDH1A1 P00352 3/20 0.57
MAPK1 P28482 3/20 0.52
KDM4E B2RXH2 3/20 0.48
RAB9A P51151 2/20 0.48
LMNA P02545 2/20 0.48
GAA P10253 1/20 0.48
ATM Q13315 1/20 0.48
NPC1 O15118 1/20 0.48
SMN1; SMN2 Q16637 1/20 0.48
TSHR P16473 3/20 0.47
MAPT P10636 2/20 0.47
POLB P06746 1/20 0.47
TP53 P04637 1/20 0.45
HTT P42858 1/20 0.45
NPSR1 Q6W5P4 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13264390 0.84 ALDH1A1 (0.61) TDP1L3MBTL1CTDSP1ALDH1A1MAPK1
SCHEMBL14470793 0.83 ALDH1A1 (0.55) TDP1L3MBTL1CTDSP1ALDH1A1MAPK1
SCHEMBL27541871 0.83 ALDH1A1 (0.55) TDP1L3MBTL1CTDSP1ALDH1A1MAPK1
SCHEMBL14280016 0.83 TDP1 (0.66) TDP1L3MBTL1CTDSP1ALDH1A1MAPK1
SCHEMBL1640414 0.79 TDP1 (0.68) TDP1L3MBTL1CTDSP1ALDH1A1MAPK1
SCHEMBL8923884 0.78 TDP1 (0.62) TDP1L3MBTL1CTDSP1ALDH1A1MAPK1
SCHEMBL27939896 0.77 TDP1 (0.58) TDP1L3MBTL1ALDH1A1MAPK1LMNA
SCHEMBL179961 0.77 ALDH1A1 (0.64) TDP1ALDH1A1MAPK1KDM4ERAB9A
SCHEMBL10036470 0.77 TDP1 (0.66) TDP1L3MBTL1CTDSP1ALDH1A1MAPK1
SCHEMBL361245 0.77 DAO (0.58) TDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3104835-B1 PULVURENT EFFERVESCENT TOPICAL TREATMENT COMPOSITION RECKITT BENCKISER LLC (US) 2019-02-13 EP disclosed
US-9877484-B2 Pulvurent effervescent topical treatment composition RECKITT BENCKISER LLC (US) 2018-01-30 US disclosed
US-20170006874-A1 PULVURENT EFFERVESCENT TOPICAL TREATMENT COMPOSITION RECKITT BENCKISER LLC (US) 2017-01-12 US disclosed
EP-3104835-A1 PULVURENT EFFERVESCENT TOPICAL TREATMENT COMPOSITION Reckitt Benckiser LLC (US) 2016-12-21 EP disclosed
WO-2015121659-A1 PULVURENT EFFERVESCENT TOPICAL TREATMENT COMPOSITION RECKITT BENCKISER LLC (US) 2015-08-20 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20170006874-A1 PULVURENT EFFERVESCENT TOPICAL TREATMENT COMPOSITION SOST, FPR2, SHH TDP1 4572/4885L3MBTL1 3586/4885CTDSP1 2418/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.