Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 3/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | AR | P10275 | 1/20 | 0.41 |
| ▸ | BUB1 | O43683 | 1/20 | 0.39 |
| ▸ | CNR2 | P34972 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | ATM | Q13315 | 1/20 | 0.36 |
| ▸ | CCNB2 | O95067 | 1/20 | 0.36 |
| ▸ | CDK1 | P06493 | 1/20 | 0.36 |
| ▸ | CCNB1 | P14635 | 1/20 | 0.36 |
| ▸ | GSK3B | P49841 | 1/20 | 0.36 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.36 |
| ▸ | CDK5R1 | Q15078 | 1/20 | 0.36 |
| ▸ | CCNB3 | Q8WWL7 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15392930 | 0.85 | ALDH1A1 (0.52) | ALDH1A1SMN1; SMN2LMNAHTTMEN1 | |
| SCHEMBL2540520 | 0.85 | BUB1 (0.49) | ALDH1A1SMN1; SMN2LMNAHTTMEN1 | |
| SCHEMBL15392921 | 0.85 | NPSR1 (0.56) | ALDH1A1SMN1; SMN2LMNAHTTMEN1 | |
| SCHEMBL23912361 | 0.85 | MAPT (0.56) | ALDH1A1LMNAHTTMEN1KMT2A | |
| SCHEMBL22084098 | 0.85 | ALDH1A1 (0.41) | ALDH1A1SMN1; SMN2LMNAHTTMEN1 | |
| SCHEMBL233377 | 0.83 | NPSR1 (0.53) | ALDH1A1SMN1; SMN2LMNAHTTMAPT | |
| SCHEMBL17010994 | 0.82 | RAPGEF4 (0.46) | ALDH1A1SMN1; SMN2HTTMEN1KMT2A | |
| SCHEMBL18002440 | 0.80 | KIF11 (0.49) | ALDH1A1SMN1; SMN2LMNAMAPTRAB9A | |
| SCHEMBL2534029 | 0.80 | KIF11 (0.49) | ALDH1A1SMN1; SMN2LMNAHTTKMT2A | |
| SCHEMBL22042451 | 0.79 | KIF11 (0.48) | ALDH1A1SMN1; SMN2LMNAHTTMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9112157-B2 | Hole transport materials including OLED applications | SOLVAY USA, INC. (US) | 2015-08-18 | — | — | US | disclosed |
| US-9112157-B2 | Hole transport materials including OLED applications | SOLVAY USA, INC. (US) | 2015-08-18 | — | — | US | disclosed |