Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAPGEF4 | Q8WZA2 | 1/20 | 0.46 |
| ▸ | KIF11 | P52732 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | HTT | P42858 | 2/20 | 0.44 |
| ▸ | RAB9A | P51151 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.39 |
| ▸ | CDK5R1 | Q15078 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | IDO1 | P14902 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.37 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17010980 | 0.82 | ALDH1A1 (0.41) | SMN1; SMN2ALDH1A1HTTRAB9AMAPT | |
| SCHEMBL22084098 | 0.81 | ALDH1A1 (0.41) | SMN1; SMN2ALDH1A1HTTMAPTMEN1 | |
| SCHEMBL15392921 | 0.81 | NPSR1 (0.56) | SMN1; SMN2ALDH1A1HTTRAB9AMAPT | |
| SCHEMBL11941052 | 0.78 | SMN1; SMN2 (0.49) | KIF11SMN1; SMN2ALDH1A1HTTRAB9A | |
| SCHEMBL15392930 | 0.78 | ALDH1A1 (0.52) | SMN1; SMN2ALDH1A1HTTMAPTMEN1 | |
| SCHEMBL23912361 | 0.78 | MAPT (0.56) | RAPGEF4ALDH1A1HTTMAPTMEN1 | |
| SCHEMBL8896899 | 0.78 | RAPGEF4 (0.67) | RAPGEF4KIF11SMN1; SMN2ALDH1A1HTT | |
| SCHEMBL4701514 | 0.76 | RAPGEF4 (0.61) | RAPGEF4KIF11SMN1; SMN2ALDH1A1HTT | |
| SCHEMBL11941058 | 0.74 | ALDH1A1 (0.43) | SMN1; SMN2ALDH1A1HTTRAB9AMAPT | |
| SCHEMBL29939003 | 0.73 | RAPGEF4 (0.54) | RAPGEF4KIF11SMN1; SMN2ALDH1A1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9112157-B2 | Hole transport materials including OLED applications | SOLVAY USA, INC. (US) | 2015-08-18 | — | — | US | disclosed |
| US-9112157-B2 | Hole transport materials including OLED applications | SOLVAY USA, INC. (US) | 2015-08-18 | — | — | US | disclosed |