Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 8/20 | 0.48 |
| ▸ | RAB9A | P51151 | 8/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 8/20 | 0.48 |
| ▸ | HPGD | P15428 | 3/20 | 0.48 |
| ▸ | MAPT | P10636 | 3/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.48 |
| ▸ | CASP1 | P29466 | 1/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
| ▸ | RECQL | P46063 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | SAE1 | Q9UBE0 | 1/20 | 0.43 |
| ▸ | UBA2 | Q9UBT2 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.43 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | RELA | Q04206 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24178752 | 0.99 | NPC1 (0.47) | NPC1RAB9ASMN1; SMN2HPGDMAPT | |
| SCHEMBL18804816 | 0.93 | NPC1 (0.51) | NPC1RAB9ASMN1; SMN2HPGDMAPT | |
| SCHEMBL18530994 | 0.90 | SMN1; SMN2 (0.47) | NPC1RAB9ASMN1; SMN2HPGDMAPT | |
| SCHEMBL12604864 | 0.89 | NPC1 (0.51) | NPC1RAB9ASMN1; SMN2HPGDMAPT | |
| SCHEMBL14001770 | 0.89 | PKM (0.48) | NPC1RAB9ASMN1; SMN2HPGDMAPT | |
| SCHEMBL25831257 | 0.87 | SMN1; SMN2 (0.50) | NPC1RAB9ASMN1; SMN2HPGDMAPT | |
| SCHEMBL4567265 | 0.86 | L3MBTL1 (0.52) | NPC1RAB9ASMN1; SMN2HPGDMAPT | |
| SCHEMBL13695374 | 0.84 | NPC1 (0.51) | NPC1RAB9ASMN1; SMN2HPGDMAPT | |
| SCHEMBL984289 | 0.84 | RAB9A (0.62) | NPC1RAB9ASMN1; SMN2HPGDMAPT | |
| SCHEMBL13411435 | 0.84 | NPC1 (0.51) | NPC1RAB9ASMN1; SMN2HPGDMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9562176-B2 | Prepolymer toughener for crack-resistant adhesives for windmills | SIKA TECHNOLOGY AG (CH) | 2017-02-07 | — | — | US | disclosed |
| US-20150232710-A1 | PREPOLYMER IMPACT RESISTOR FOR CRACK-RESISTANT ADHESIVES FOR WINDMILLS | SIKA TECHNOLOGY AG (CH) | 2015-08-20 | — | — | US | disclosed |