Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 8/20 | 0.47 |
| ▸ | RAB9A | P51151 | 8/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 8/20 | 0.47 |
| ▸ | HPGD | P15428 | 3/20 | 0.47 |
| ▸ | MAPT | P10636 | 3/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.47 |
| ▸ | CASP1 | P29466 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | RECQL | P46063 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.42 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | RELA | Q04206 | 1/20 | 0.42 |
| ▸ | ACHE | P22303 | 6/20 | 0.42 |
| ▸ | SAE1 | Q9UBE0 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17013151 | 0.99 | NPC1 (0.48) | NPC1RAB9ASMN1; SMN2HPGDMAPT | |
| SCHEMBL18804816 | 0.94 | NPC1 (0.51) | NPC1RAB9ASMN1; SMN2HPGDMAPT | |
| SCHEMBL18530994 | 0.88 | SMN1; SMN2 (0.47) | NPC1RAB9ASMN1; SMN2HPGDMAPT | |
| SCHEMBL14001770 | 0.87 | PKM (0.48) | NPC1RAB9ASMN1; SMN2HPGDMAPT | |
| SCHEMBL12604864 | 0.87 | NPC1 (0.51) | NPC1RAB9ASMN1; SMN2HPGDMAPT | |
| SCHEMBL25831257 | 0.86 | SMN1; SMN2 (0.50) | NPC1RAB9ASMN1; SMN2HPGDMAPT | |
| SCHEMBL19402843 | 0.85 | NPC1 (0.56) | NPC1RAB9ASMN1; SMN2HPGDMAPT | |
| SCHEMBL4567265 | 0.84 | L3MBTL1 (0.52) | NPC1RAB9ASMN1; SMN2HPGDMAPT | |
| SCHEMBL10595628 | 0.84 | RAB9A (0.61) | NPC1RAB9ASMN1; SMN2HPGDMAPT | |
| SCHEMBL985616 | 0.84 | RAB9A (0.61) | NPC1RAB9ASMN1; SMN2HPGDMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220002234-A1 | PRODUCTION METHOD FOR ISOCYANATE COMPOUND | NATIONAL UNIVERSITY CORPORATION KOBE UNIVERSITY (JP) | 2022-01-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220002234-A1 | PRODUCTION METHOD FOR ISOCYANATE COMPOUND | IDH2, CBR3, IDH3A | NPC1 1444/4885RAB9A 2522/4885SMN1; SMN2 4459/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.