Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | HCK | P08631 | 5/20 | 0.36 |
| ▸ | MAPK12 | P53778 | 5/20 | 0.36 |
| ▸ | MAPK14 | Q16539 | 5/20 | 0.36 |
| ▸ | SRC | P12931 | 2/20 | 0.36 |
| ▸ | CTSV | O60911 | 2/20 | 0.36 |
| ▸ | CTSL | P07711 | 2/20 | 0.36 |
| ▸ | PTGES | O14684 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 2/20 | 0.34 |
| ▸ | RAB9A | P51151 | 2/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | MYC | P01106 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 3/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31086801 | 0.90 | LMNA (0.41) | ALDH1A1LMNAHCKMAPK12MAPK14 | |
| SCHEMBL17008473 | 0.90 | LMNA (0.41) | ALDH1A1LMNAHCKMAPK12MAPK14 | |
| SCHEMBL31086726 | 0.90 | CTSV (0.39) | ALDH1A1LMNAHCKMAPK12MAPK14 | |
| SCHEMBL17008509 | 0.90 | CTSV (0.39) | ALDH1A1LMNAHCKMAPK12MAPK14 | |
| SCHEMBL17008492 | 0.88 | ALDH1A1 (0.39) | ALDH1A1LMNAHCKMAPK12MAPK14 | |
| SCHEMBL31086600 | 0.87 | LMNA (0.40) | ALDH1A1LMNAHCKMAPK12MAPK14 | |
| SCHEMBL17008491 | 0.87 | LMNA (0.40) | ALDH1A1LMNAHCKMAPK12MAPK14 | |
| SCHEMBL17014136 | 0.85 | HCK (0.37) | HCKMAPK12MAPK14SRCSMN1; SMN2 | |
| SCHEMBL17017528 | 0.84 | HCK (0.35) | HCKMAPK12MAPK14SRCSMN1; SMN2 | |
| SCHEMBL31086607 | 0.84 | HCK (0.35) | HCKMAPK12MAPK14SRCSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11634406-B2 | Inhibitor of p38 MAP kinase | RESPIVERT LTD. (GB) | 2023-04-25 | — | — | US | disclosed |
| US-20210179584-A1 | INHIBITOR OF p38 MAP KINASE | RESPIVERT LIMITED (GB) | 2021-06-17 | — | — | US | disclosed |
| US-10815217-B2 | Inhibitor of p38 MAP kinase | RESPIVERT LTD. (GB) | 2020-10-27 | — | — | US | disclosed |
| EP-3357919-B1 | AROMATIC HETEROCYCLIC COMPOUNDS AS ANTIINFLAMMATORY COMPOUNDS | RESPIVERT LTD (GB) | 2019-11-20 | — | — | EP | disclosed |
| US-20190092752-A1 | INHIBITOR OF p38 MAP KINASE | TOPIVERT PHARMA LTD. (GB) | 2019-03-28 | — | — | US | disclosed |
| EP-3357919-A1 | AROMATIC HETEROCYCLIC COMPOUNDS AS ANTIINFLAMMATORY COMPOUNDS | Respivert Limited (GB) | 2018-08-08 | — | — | EP | disclosed |
| EP-3105222-B1 | AROMATIC HETEROCYCLIC COMPOUNDS AS ANTIINFLAMMATORY COMPOUNDS | RESPIVERT LTD (GB) | 2018-04-11 | — | — | EP | disclosed |
| US-20170182039-A1 | INHIBITOR OF p38 MAP KINASE | TOPIVERT PHARMA LTD. (GB) | 2017-06-29 | — | — | US | disclosed |
| US-20170182039-A1 | INHIBITOR OF p38 MAP KINASE | TOPIVERT PHARMA LTD. (GB) | 2017-06-29 | — | — | US | disclosed |
| US-9624196-B2 | Inhibitor of p38 MAP kinase | RESPIVERT LTD. (GB) | 2017-04-18 | — | — | US | disclosed |
| US-9624196-B2 | Inhibitor of p38 MAP kinase | RESPIVERT LTD. (GB) | 2017-04-18 | — | — | US | disclosed |
| US-20160368896-A1 | INHIBITOR OF p38 MAP KINASE | RESPIVERT LIMITED (GB) | 2016-12-22 | — | — | US | disclosed |
| US-20160368896-A1 | INHIBITOR OF p38 MAP KINASE | RESPIVERT LIMITED (GB) | 2016-12-22 | — | — | US | disclosed |
| US-9447076-B2 | Inhibitor of p38 map kinase | RESPIVERT LTD. (GB) | 2016-09-20 | — | — | US | disclosed |
| US-9447076-B2 | Inhibitor of p38 map kinase | RESPIVERT LTD. (GB) | 2016-09-20 | — | — | US | disclosed |
| WO-2015121444-A1 | AROMATIC HETEROCYCLIC COMPOUNDS AS ANTIINFLAMMATORY COMPOUNDS | RESPIVERT LIMITED (GB) | 2015-08-20 | — | — | WO | disclosed |
| US-20150232450-A1 | INHIBITOR OF p38 MAP KINASE | RESPIVERT LIMITED (GB) | 2015-08-20 | — | — | US | disclosed |
| US-20150232450-A1 | INHIBITOR OF p38 MAP KINASE | RESPIVERT LIMITED (GB) | 2015-08-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170182039-A1 | INHIBITOR OF p38 MAP KINASE | MAPK1, MAPKAPK2, MAP3K1 | ALDH1A1 2697/4885LMNA 1566/4885HCK 274/4885 |
| US-10815217-B2 | Inhibitor of p38 MAP kinase | MAPK1, MAPKAPK2, MAP3K1 | ALDH1A1 2697/4885LMNA 1566/4885HCK 274/4885 |
| US-20210179584-A1 | INHIBITOR OF p38 MAP KINASE | MAPK1, MAPKAPK2, MAPK10 | ALDH1A1 1810/4885LMNA 3181/4885HCK 812/4885 |
| US-20160368896-A1 | INHIBITOR OF p38 MAP KINASE | MAPK1, MAPK4, MAPK8 | ALDH1A1 2523/4885LMNA 2165/4885HCK 678/4885 |
| US-11634406-B2 | Inhibitor of p38 MAP kinase | MAPK1, MAPKAPK2, MAPK10 | ALDH1A1 1810/4885LMNA 3181/4885HCK 812/4885 |
| US-20150232450-A1 | INHIBITOR OF p38 MAP KINASE | MAPK1, MAPKAPK2, MAPK10 | ALDH1A1 1810/4885LMNA 3181/4885HCK 812/4885 |
| US-20190092752-A1 | INHIBITOR OF p38 MAP KINASE | MAPK1, MAPKAPK2, MAP3K1 | ALDH1A1 2697/4885LMNA 1566/4885HCK 274/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.