Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.59 |
| ▸ | MAPT | P10636 | 2/20 | 0.59 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.59 |
| ▸ | ATM | Q13315 | 1/20 | 0.59 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.59 |
| ▸ | BIRC2 | Q13490 | 1/20 | 0.54 |
| ▸ | REN | P00797 | 3/20 | 0.53 |
| ▸ | MME | P08473 | 2/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.53 |
| ▸ | THRB | P10828 | 1/20 | 0.53 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.53 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.53 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.53 |
| ▸ | MEN1 | O00255 | 1/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.53 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15223640 | 1.00 | POLB (0.59) | POLBMAPTNPSR1ATMTDP1 | |
| SCHEMBL15223643 | 0.91 | ALDH1A1 (0.64) | POLBMAPTNPSR1ATMTDP1 | |
| SCHEMBL15223637 | 0.90 | ALDH1A1 (0.60) | POLBMAPTNPSR1ATMTDP1 | |
| SCHEMBL10880443 | 0.89 | POLB (0.58) | POLBMAPTNPSR1ATMTDP1 | |
| SCHEMBL15222238 | 0.88 | POLB (0.57) | POLBMAPTNPSR1ATMTDP1 | |
| SCHEMBL9813890 | 0.88 | POLB (0.57) | POLBMAPTNPSR1ATMTDP1 | |
| SCHEMBL15223599 | 0.87 | ALDH1A1 (0.69) | BIRC2MMEALDH1A1THRBCYP2C9 | |
| SCHEMBL10880715 | 0.87 | REN (0.70) | POLBMAPTNPSR1ATMTDP1 | |
| SCHEMBL25533190 | 0.87 | POLB (0.56) | POLBMAPTNPSR1ATMTDP1 | |
| SCHEMBL10878382 | 0.86 | MMP8 (0.57) | POLBMAPTNPSR1ATMTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170247324-A1 | ALDEHYDE CAPTURE LIGATION TECHNOLOGY FOR SYNTHESIS OF AMIDE BONDS | UNIV NEW YORK (US) | 2017-08-31 | — | — | US | disclosed |
| US-9593142-B2 | Aldehyde capture ligation technology for synthesis of amide bonds | NEW YORK UNIVERSITY (US) | 2017-03-14 | — | — | US | disclosed |
| US-20150232504-A1 | ALDEHYDE CAPTURE LIGATION TECHNOLOGY FOR SYNTHESIS OF AMIDE BONDS | NEW YORK UNIVERSITY (US) | 2015-08-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170247324-A1 | ALDEHYDE CAPTURE LIGATION TECHNOLOGY FOR SYNTHESIS OF AMIDE BONDS | ALDH3A1, ALDH2, ALDH1A1 | POLB 887/4885MAPT 4097/4885NPSR1 2609/4885 |
| US-20150232504-A1 | ALDEHYDE CAPTURE LIGATION TECHNOLOGY FOR SYNTHESIS OF AMIDE BONDS | ALDH3A1, ALDH2, ALDH1A1 | POLB 887/4885MAPT 4097/4885NPSR1 2609/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.