Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TYMP | P19971 | 3/20 | 0.47 |
| ▸ | PKM | P14618 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | TK1 | P04183 | 4/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | TK2 | O00142 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17016481 | 0.82 | PKM (0.50) | TYMPPKMMAPK1TK1HPGD | |
| SCHEMBL18358008 | 0.81 | PKM (0.45) | TYMPPKMMAPK1TK1HPGD | |
| SCHEMBL17016484 | 0.79 | DUT (0.51) | TYMPPKMMAPK1TK1HPGD | |
| SCHEMBL17016710 | 0.77 | TK1 (0.52) | TYMPPKMMAPK1TK1HPGD | |
| SCHEMBL17016482 | 0.77 | PKM (0.45) | TYMPPKMMAPK1TK1HPGD | |
| SCHEMBL16485723 | 0.75 | TK1 (0.42) | TYMPMAPK1TK1HPGD | |
| SCHEMBL16263428 | 0.74 | TK2 (0.53) | TYMPMAPK1TK1HPGDTK2 | |
| SCHEMBL16263427 | 0.74 | MAPK1 (0.48) | TYMPMAPK1TK1HPGDTK2 | |
| SCHEMBL18357541 | 0.72 | MAPK1 (0.49) | TYMPMAPK1TK1HPGD | |
| SCHEMBL17016636 | 0.71 | TK1 (0.46) | TYMPMAPK1TK1HPGDTK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170000712-A1 | SUNLESS TANNING COMPOUNDS AND COMPOSITIONS | REGENTS OF THE UNIVERSITY OF MINNESOTA (US) | 2017-01-05 | — | — | US | disclosed |
| US-9364406-B2 | Open chained or fused 1,1′-alkylene-bis-uracil derivatives, useful in skin UV-protection | REGENTS OF THE UNIVERSITY OF MINNESOTA (US) | 2016-06-14 | — | — | US | disclosed |
| US-20150231051-A1 | OPEN CHAINED OR FUSED 1,1 '-ALKYLENE-BIS-URACIL DERIVATIVES, USEFUL IN SKIN UV-PROTECTION | REGENTS OF THE UNIVERSITY OF MINNESOTA (US) | 2015-08-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170000712-A1 | SUNLESS TANNING COMPOUNDS AND COMPOSITIONS | TYR, SUN2, ERCC4 | TYMP 1884/4885PKM 4543/4885MAPK1 1383/4885 |
| US-20150231051-A1 | OPEN CHAINED OR FUSED 1,1 '-ALKYLENE-BIS-URACIL DERIVATIVES, USEFUL IN SKIN UV-PROTECTION | UNG, ERCC1, ERCC2 | TYMP 115/4885PKM 4075/4885MAPK1 1573/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.