Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TK1 | P04183 | 5/20 | 0.52 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | TYMP | P19971 | 3/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | DUT | P33316 | 3/20 | 0.41 |
| ▸ | RNASE1 | P07998 | 1/20 | 0.41 |
| ▸ | TK2 | O00142 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17013802 | 0.92 | TK1 (0.59) | TK1HPGDTYMPMAPK1RNASE1 | |
| SCHEMBL16485723 | 0.83 | TK1 (0.42) | TK1HPGDTYMPMAPK1DUT | |
| SCHEMBL17016636 | 0.82 | TK1 (0.46) | TK1HPGDTYMPMAPK1DUT | |
| SCHEMBL17016484 | 0.80 | DUT (0.51) | TK1HPGDTYMPMAPK1PKM | |
| SCHEMBL17016481 | 0.79 | PKM (0.50) | TK1HPGDTYMPMAPK1PKM | |
| SCHEMBL17016708 | 0.77 | TYMP (0.47) | TK1HPGDTYMPMAPK1PKM | |
| SCHEMBL17016482 | 0.76 | PKM (0.45) | TK1HPGDTYMPMAPK1PKM | |
| SCHEMBL16485703 | 0.74 | TYMP (0.58) | TK1HPGDTYMPMAPK1 | |
| SCHEMBL16263555 | 0.74 | TK1 (0.47) | TK1HPGDMAPK1DUTTK2 | |
| SCHEMBL17016638 | 0.74 | TK1 (0.42) | TK1HPGDMAPK1DUT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9364406-B2 | Open chained or fused 1,1′-alkylene-bis-uracil derivatives, useful in skin UV-protection | REGENTS OF THE UNIVERSITY OF MINNESOTA (US) | 2016-06-14 | — | — | US | disclosed |
| US-20150231051-A1 | OPEN CHAINED OR FUSED 1,1 '-ALKYLENE-BIS-URACIL DERIVATIVES, USEFUL IN SKIN UV-PROTECTION | REGENTS OF THE UNIVERSITY OF MINNESOTA (US) | 2015-08-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150231051-A1 | OPEN CHAINED OR FUSED 1,1 '-ALKYLENE-BIS-URACIL DERIVATIVES, USEFUL IN SKIN UV-PROTECTION | UNG, ERCC1, ERCC2 | TK1 102/4885HPGD 643/4885TYMP 115/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.