Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR6 | P46095 | 8/20 | 0.40 |
| ▸ | WHR1 | P49842 | 3/20 | 0.37 |
| ▸ | RET | P07949 | 2/20 | 0.36 |
| ▸ | ROS1 | P08922 | 2/20 | 0.36 |
| ▸ | FLT3 | P36888 | 2/20 | 0.36 |
| ▸ | EML4 | Q9HC35 | 2/20 | 0.36 |
| ▸ | ALK | Q9UM73 | 2/20 | 0.36 |
| ▸ | SLC2A1 | P11166 | 2/20 | 0.36 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.36 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.36 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.36 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.35 |
| ▸ | DPP4 | P27487 | 1/20 | 0.34 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.34 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL194991 | 0.91 | PDE4D (0.35) | RETROS1FLT3EML4ALK | |
| Trifluoroacetic Acid SCHEMBL16924607 | 0.82 | GPR6 (0.35) | GPR6WHR1RETROS1FLT3 | |
| SCHEMBL8051590 | 0.82 | PDE4D (0.36) | PDE4D | |
| SCHEMBL10265576 | 0.81 | EML4 (0.36) | RETROS1FLT3EML4ALK | |
| SCHEMBL589081 | 0.81 | MAPT (0.38) | RETROS1FLT3EML4ALK | |
| Trifluoroacetic Acid SCHEMBL15808520 | 0.80 | SLC2A1 (0.36) | SLC2A1ITGB3ITGA2B | |
| SCHEMBL187336 | 0.79 | GPR6 (0.38) | GPR6PDE4D | |
| SCHEMBL9268585 | 0.79 | CSNK1D (0.38) | ALK | |
| Trifluoroacetic Acid SCHEMBL15808556 | 0.79 | SLC2A1 (0.35) | GPR6WHR1SLC2A1ITGB3ITGA2B | |
| SCHEMBL589617 | 0.79 | LMNA (0.43) | EML4ALKPDE4D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9115142-B2 | Heterocycle-substituted piperazino-dihydrothienopyrimidines | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2015-08-25 | — | — | US | disclosed |