SCHEMBL17020174

SCHEMBL17020174

Cc1cc(C=O)cc(C)c1-n1c2ccc(Cl)cc2c2cc(Cl)ccc21

nearest known ligand 0.52

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
PTGER4 P35408 1/20 0.52
LMNA P02545 3/20 0.38
HSD17B10 Q99714 2/20 0.37
TP53 P04637 1/20 0.35
SMN1; SMN2 Q16637 1/20 0.35
GFER P55789 1/20 0.35
ACLY P53396 1/20 0.34
ALDH1A1 P00352 5/20 0.33
HPGD P15428 2/20 0.33
ALDH1A3 P47895 1/20 0.33
KDM4E B2RXH2 1/20 0.33
MAPT P10636 1/20 0.33
MAPK1 P28482 1/20 0.33
TDP1 Q9NUW8 1/20 0.33
CYP2A6 P11509 1/20 0.33
PTGS2 P35354 2/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17020175 0.81 ALDH1A1 (0.37) PTGER4LMNASMN1; SMN2ALDH1A1ALDH1A3
SCHEMBL17020173 0.79 PTGER4 (0.42) PTGER4LMNAALDH1A1HPGDALDH1A3
SCHEMBL17020177 0.72 ALDH1A1 (0.37) ALDH1A1ALDH1A3CYP2A6
SCHEMBL11453067 0.69 PTGER4 (1.00) PTGER4LMNAHSD17B10TP53SMN1; SMN2
SCHEMBL7603554 0.68 RAB9A (0.52) PTGER4LMNASMN1; SMN2GFERALDH1A1
SCHEMBL15201560 0.67 PTGER4 (0.47) PTGER4LMNAHSD17B10SMN1; SMN2ALDH1A1
SCHEMBL16423639 0.66 HSD17B10 (0.50) LMNAHSD17B10SMN1; SMN2ALDH1A1KDM4E
Tert-Butyl Formate SCHEMBL27591631 0.66 TDP1 (0.37) PTGER4HSD17B10GFERACLYALDH1A1
SCHEMBL14962875 0.65 CSNK2A2 (0.38) HSD17B10TP53ALDH1A1HPGDKDM4E
SCHEMBL2235190 0.65 CYP3A4 (0.46) HSD17B10SMN1; SMN2ALDH1A1ALDH1A3KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2015121239-A1 ORGANIC MOLECULE HAVING SMALL TRIPLET-SINGLET ENERGY SPACINGS FOR EFFECTIVE DELAYED FLUORESCENCE FOR APPLICATION IN OPTOELECTRONIC DEVICES YERSIN HARTMUT (DE) 2015-08-20 WO disclosed