SCHEMBL17020177

SCHEMBL17020177

Cc1cc(C=O)cc(C)c1-n1c2cc(Br)ccc2c2ccc(Br)cc21

nearest known ligand 0.37

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.37
CYP2A6 P11509 2/20 0.34
ALDH1A3 P47895 3/20 0.33
ERN1 O75460 2/20 0.33
PDGFRA P16234 1/20 0.33
CDK5 Q00535 1/20 0.33
TYRO3 Q06418 1/20 0.33
SRC P12931 1/20 0.32
EGLN1 Q9GZT9 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17020175 0.88 ALDH1A1 (0.37) ALDH1A1CYP2A6ALDH1A3ERN1SRC
SCHEMBL17020173 0.79 PTGER4 (0.42) ALDH1A1ALDH1A3
SCHEMBL13701302 0.76 ALDH1A1 (0.40) ALDH1A1CYP2A6ALDH1A3ERN1PDGFRA
SCHEMBL17020174 0.72 PTGER4 (0.52) ALDH1A1CYP2A6ALDH1A3
SCHEMBL11186554 0.69 PTGER4 (0.52) ALDH1A1CYP2A6ALDH1A3SRC
SCHEMBL27120040 0.67 TSHR (0.41) ALDH1A1
SCHEMBL19269076 0.66 KDM4E (0.42) ALDH1A1
SCHEMBL24811505 0.66 PTGER4 (0.63) ALDH1A1ALDH1A3SRC
SCHEMBL30958190 0.66 PTGER4 (0.63) ALDH1A1ALDH1A3SRC
SCHEMBL15946330 0.66 TSPO (0.43) ALDH1A1CYP2A6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2015121239-A1 ORGANIC MOLECULE HAVING SMALL TRIPLET-SINGLET ENERGY SPACINGS FOR EFFECTIVE DELAYED FLUORESCENCE FOR APPLICATION IN OPTOELECTRONIC DEVICES YERSIN HARTMUT (DE) 2015-08-20 WO disclosed