Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 1/20 | 0.46 |
| ▸ | CA9 | Q16790 | 1/20 | 0.46 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.44 |
| ▸ | MAOA | P21397 | 3/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | GAA | P10253 | 3/20 | 0.43 |
| ▸ | RAB9A | P51151 | 2/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.42 |
| ▸ | TUBB | P07437 | 1/20 | 0.42 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.42 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.42 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.42 |
| ▸ | TUBB4B | P68371 | 1/20 | 0.42 |
| ▸ | TUBB3 | Q13509 | 1/20 | 0.42 |
| ▸ | TUBB2A | Q13885 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7043680 | 0.94 | TNFSF11 (0.51) | CA12CA9TSHRTUBB4ATUBB | |
| SCHEMBL6717966 | 0.89 | TYR (0.60) | CA12CA9SLC22A6MAOAKDM4E | |
| SCHEMBL9735764 | 0.89 | KDM4E (0.40) | CA12CA9SLC22A6MAOAKDM4E | |
| SCHEMBL9736443 | 0.89 | KDM4E (0.40) | CA12CA9SLC22A6MAOAKDM4E | |
| SCHEMBL19186866 | 0.89 | S1PR1 (0.44) | CA12CA9SLC22A6MAOAKDM4E | |
| SCHEMBL9442085 | 0.88 | BACE1 (0.42) | SLC22A6MAOAKDM4EALDH1A1GAA | |
| SCHEMBL9413340 | 0.88 | ACHE (0.47) | CA12CA9SLC22A6MAOAKDM4E | |
| SCHEMBL1702125 | 0.88 | BACE1 (0.42) | CA12CA9SLC22A6MAOAKDM4E | |
| SCHEMBL23417682 | 0.88 | CA12 (0.38) | CA12CA9SLC22A6MAOAKDM4E | |
| SCHEMBL27454439 | 0.87 | CSNK2A1 (0.47) | CA12CA9SLC22A6MAOAKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 386 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10292921-B2 | Hair dyeing process using a composition comprising at least one indol(in)e compound and a polycyclic aromatic compound containing at least ten carbon atoms | L'OREAL (FR) | 2019-05-21 | — | — | US | claimed |
| US-20180092822-A1 | HAIR DYEING PROCESS USING A COMPOSITION COMPRISING AT LEAST ONE INDOL(IN)E COMPOUND AND A POLYCYCLIC AROMATIC COMPOUND CONTAINING AT LEAST TEN CARBON ATOMS | L'OREAL (FR) | 2018-04-05 | — | — | US | claimed |
| EP-2582351-B1 | HAIR DYEING PROCESS USING A COMPOSITION COMPRISING AT LEAST ONE INDOLE OR INDOLINE COMPOUND, A METAL SALT, HYDROGEN PEROXIDE AND A BASIFYING AGENT | L'ORÉAL (FR) | 2017-08-02 | — | — | EP | claimed |
| EP-3148648-A1 | HAIR DYEING PROCESS USING A COMPOSITION COMPRISING AT LEAST ONE INDOL(IN)E COMPOUND AND A POLYCYCLIC AROMATIC COMPOUND CONTAINING AT LEAST TEN CARBON ATOMS | L'OREAL (FR) | 2017-04-05 | — | — | EP | claimed |
| WO-2015181244-A1 | HAIR DYEING PROCESS USING A COMPOSITION COMPRISING AT LEAST ONE INDOL(IN)E COMPOUND AND A POLYCYCLIC AROMATIC COMPOUND CONTAINING AT LEAST TEN CARBON ATOMS | L'OREAL (FR) | 2015-12-03 | — | — | WO | claimed |
| EP-0971682-B2 | DYEING COMPOSITION FOR KERATIN FIBRES AND DYEING METHOD USING SAME | OREAL (FR) | 2009-09-23 | — | — | EP | claimed |
| EP-1464323-B1 | Fluorescent dye composition for human keratin fibres | OREAL (FR) | 2006-12-13 | — | — | EP | claimed |
| CN-1202802-C | Dyeing composition for keratin fibres and dyeing method using said composition | OREAL (FR) | 2005-05-25 | — | — | CN | claimed |
| EP-1464323-A1 | Fluorescent dye composition for human keratin fibres | L'OREAL (FR) | 2004-10-06 | — | — | EP | claimed |
| CN-1160049-C | Oxidation dyeing for keratin fibres | �ź㴫 | 2004-08-04 | — | — | CN | claimed |
| WO-1993002655-A1 | PROCESS FOR THE TEMPORARY DYEING OF KERATIN FIBRES INVOLVING AN INSOLUBLE PIGMENT OBTAINED BY THE OXIDATIVE POLYMERISATION OF INDOLE DERIVATIVES | L'OREAL (FR) | 1993-02-18 | — | — | WO | claimed |
| WO-1993000068-A1 | METHOD FOR PREPARING SUBMICRON PARTICLES IN THE PRESENCE OF LIPID VESICLES, AND CORRESPONDING COMPOSITIONS | L'OREAL (FR) | 1993-01-07 | — | — | WO | claimed |
| EP-0518773-A1 | Cosmetic composition containing a blend of metallic oxids nanopigments and melanic pigments | L'OREAL (FR) | 1992-12-16 | — | — | EP | claimed |
| EP-0504347-A1 | COSMETIC COMPOSITION COMPRISING A DISPERSION OF LIPIDIC VESICLES AS WELL AS MELANIC PIGMENTS. | OREAL (FR) | 1992-09-23 | — | — | EP | claimed |
| US-5126125-A | Decreasing the melanin content in mammalian skin and hair using 5,6-dihydroxindole derivatives | YALE UNIVERSITY (US) | 1992-06-30 | — | — | US | claimed |
| WO-1992005761-A1 | COSMETIC COMPOSITION COMPRISING A DISPERSION OF LIPIDIC VESICLES AS WELL AS MELANIC PIGMENTS | L'OREAL (FR) | 1992-04-16 | — | — | WO | claimed |
| EP-0467767-A1 | Product based on flaky particles containing melanine pigment and process for their preparation | L'OREAL (FR) | 1992-01-22 | — | — | EP | claimed |
| US-5049381-A | Skin coloring compositions containing indoles and quaternary ammonium salts | CLAIROL INCORPORATED (US) | 1991-09-17 | — | — | US | claimed |
| US-5037640-A | Protective coating against ultraviolet radiation | CLAIROL INCORPORATED (US) | 1991-08-06 | — | — | US | claimed |
| US-4932977-A | Indole-aldehyde hair dyes | CLAIROL INCORPORATED (US) | 1990-06-12 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180092822-A1 | HAIR DYEING PROCESS USING A COMPOSITION COMPRISING AT LEAST ONE INDOL(IN)E COMPOUND AND A POLYCYCLIC AROMATIC COMPOUND CONTAINING AT LEAST TEN CARBON ATOMS | KRT18, TYR, INCENP | CA12 212/4885CA9 519/4885SLC22A6 2007/4885 |
| US-10292921-B2 | Hair dyeing process using a composition comprising at least one indol(in)e compound and a polycyclic aromatic compound containing at least ten carbon atoms | KRT18, TYR, INCENP | CA12 226/4885CA9 568/4885SLC22A6 1941/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.