Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMO | O15229 | 2/20 | 0.73 |
| ▸ | PRKDC | P78527 | 2/20 | 0.60 |
| ▸ | HPGD | P15428 | 2/20 | 0.57 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.53 |
| ▸ | MEN1 | O00255 | 4/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.53 |
| ▸ | GAA | P10253 | 1/20 | 0.53 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.53 |
| ▸ | PIK3CA | P42336 | 2/20 | 0.52 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.52 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.52 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.52 |
| ▸ | RAB9A | P51151 | 3/20 | 0.52 |
| ▸ | AOC3 | Q16853 | 2/20 | 0.52 |
| ▸ | MAPT | P10636 | 2/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.50 |
| ▸ | NPC1 | O15118 | 1/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3722032 | 0.87 | KMO (0.58) | KMOPRKDCHPGDSCN9AKMT2A | |
| SCHEMBL1505190 | 0.86 | KMO (0.61) | KMOPRKDCHPGDKMT2AMEN1 | |
| SCHEMBL2346130 | 0.85 | MAPT (0.62) | SCN9AKMT2AMEN1ALDH1A1KDM4E | |
| SCHEMBL30634127 | 0.84 | KMO (1.00) | KMOPRKDCHPGDKMT2AMEN1 | |
| SCHEMBL65857 | 0.84 | KMO (1.00) | KMOPRKDCHPGDKMT2AMEN1 | |
| SCHEMBL6374645 | 0.84 | KMO (0.61) | KMOPRKDCHPGDKMT2AMEN1 | |
| SCHEMBL17915624 | 0.84 | KMO (0.59) | KMOPRKDCHPGDKMT2AMEN1 | |
| SCHEMBL4248924 | 0.83 | HPGD (0.73) | KMOHPGDKMT2AMEN1ALDH1A1 | |
| SCHEMBL31554953 | 0.81 | HRH3 (0.60) | KMOHPGDALDH1A1RAB9ASMN1; SMN2 | |
| SCHEMBL4245858 | 0.81 | HPGD (0.74) | KMOPRKDCHPGDKMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025093558-A1 | ANTIVIRAL COMPOUNDS AND COMPOSITIONS THEREFROM | CONSEJO SUPERIOR DE INVESTIGACIONES CIENTÍFICAS (ES) | 2025-05-08 | — | — | WO | disclosed |
| US-9855260-B2 | Quinolinone derivatives | GLAXOSMITHKLINE LLC (US) | 2018-01-02 | — | — | US | disclosed |
| US-20150238480-A1 | QUINOLINONE DERIVATIVES | GLAXOSMITHKLINE LLC | 2015-08-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150238480-A1 | QUINOLINONE DERIVATIVES | PRKAG2, PRKAB2, PRKAG1 | KMO 3830/4885PRKDC 381/4885HPGD 621/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.