Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 3/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.34 |
| ▸ | HSD17B1 | P14061 | 1/20 | 0.33 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.33 |
| ▸ | APP | P05067 | 1/20 | 0.33 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.32 |
| ▸ | RPS6KA2 | Q15349 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 2/20 | 0.31 |
| ▸ | ACHE | P22303 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17734613 | 0.92 | ESR2 (0.39) | L3MBTL1MAPTESR2HSD17B1HSD17B2 | |
| SCHEMBL11330854 | 0.91 | PTPRC (0.34) | CYP3A4ALDH1A1CYP1A2MAPTCYP2C19 | |
| SCHEMBL11330069 | 0.91 | HSD17B1 (0.35) | CYP3A4ESR2HSD17B1HSD17B2LMNA | |
| SCHEMBL17734616 | 0.89 | ESR2 (0.37) | L3MBTL1KDM4EMAPTESR2HSD17B1 | |
| SCHEMBL11321702 | 0.88 | HSD17B1 (0.36) | CYP3A4ALDH1A1CYP1A2MAPTCYP2C9 | |
| SCHEMBL1702523 | 0.87 | ALDH1A1 (0.46) | CYP3A4ALDH1A1L3MBTL1KDM4ECYP1A2 | |
| SCHEMBL8943827 | 0.87 | ALDH1A1 (0.44) | CYP3A4ALDH1A1L3MBTL1KDM4ECYP1A2 | |
| SCHEMBL17734603 | 0.85 | ESR2 (0.42) | CYP3A4ALDH1A1L3MBTL1KDM4ECYP1A2 | |
| SCHEMBL17734599 | 0.85 | CYP2A6 (0.37) | ALDH1A1L3MBTL1CYP1A2TDP1ESR2 | |
| SCHEMBL17734621 | 0.85 | KMT2A (0.31) | HSD17B1HSD17B2KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 135 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20150037732-A1 | METHOD FOR MANUFACTURING PHOTORECEPTOR LAYERS | XEROX CORPORATION (US) | 2015-02-05 | — | — | US | claimed |
| US-7267917-B2 | Photoreceptor charge transport layer composition | XEROX CORPORATION (US) | 2007-09-11 | — | — | US | claimed |
| US-20060063080-A1 | Photoreceptor charge transport layer composition | XEROX CORPORATION (US) | 2006-03-23 | — | — | US | claimed |
| US-6645686-B1 | Electrophotographic imaging members | XEROX CORPORATION | 2003-11-11 | — | — | US | claimed |
| US-5610213-A | POLYSILOXANES | GENERAL ELECTRIC COMPANY (US) | 1997-03-11 | — | — | US | claimed |
| US-4299897-A | Aromatic amino charge transport layer in electrophotography | XEROX CORPORATION (US) | 1981-11-10 | — | — | US | claimed |
| US-4047948-A | Composite layered imaging member for electrophotography | XEROX CORPORATION (US) | 1977-09-13 | — | — | US | claimed |
| US-20160133847-A1 | AROMATIC AMINE DERIVATIVE AND ORGANIC ELECTROLUMINESCENT ELEMENT | IDEMITSU KOSAN CO., LTD. (JP) | 2016-05-12 | — | — | US | disclosed |
| US-20160133847-A1 | AROMATIC AMINE DERIVATIVE AND ORGANIC ELECTROLUMINESCENT ELEMENT | IDEMITSU KOSAN CO., LTD. (JP) | 2016-05-12 | — | — | US | disclosed |
| US-20150037732-A1 | METHOD FOR MANUFACTURING PHOTORECEPTOR LAYERS | XEROX CORPORATION (US) | 2015-02-05 | — | — | US | disclosed |
| EP-1089130-B1 | Process for fabricating an electrophotographic imaging member | XEROX CORP (US) | 2012-04-18 | — | — | EP | disclosed |
| US-7811728-B2 | Imaging members and process for preparing same | XEROX CORPORATION (US) | 2010-10-12 | — | — | US | disclosed |
| US-7704656-B2 | Photoconductive imaging member | XEROX CORPORATION (US) | 2010-04-27 | — | — | US | disclosed |
| US-4427452-A | SILANE-TREATED KAOLINIC CLAY | ENGLISH CLAYS LOVERING POCHIN & COMPANY LIMITED (GB) | 1984-01-24 | — | — | US | disclosed |
| US-4299897-A | Aromatic amino charge transport layer in electrophotography | XEROX CORPORATION (US) | 1981-11-10 | — | — | US | disclosed |
| US-4281054-A | Overcoated photoreceptor containing injecting contact | XEROX CORPORATION (US) | 1981-07-28 | — | — | US | disclosed |
| US-4081274-A | Composite layered photoreceptor | XEROX CORPORATION (US) | 1978-03-28 | — | — | US | disclosed |
| US-4078925-A | Composite layered photoreceptor | XEROX CORPORATION (US) | 1978-03-14 | — | — | US | disclosed |
| US-4047948-A | Composite layered imaging member for electrophotography | XEROX CORPORATION (US) | 1977-09-13 | — | — | US | disclosed |
| US-4047949-A | Composite layered imaging member for electrophotography | XEROX CORPORATION (US) | 1977-09-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160133847-A1 | AROMATIC AMINE DERIVATIVE AND ORGANIC ELECTROLUMINESCENT ELEMENT | ARL1, CCNL2, APOL1 | CYP3A4 1604/4885ALDH1A1 466/4885L3MBTL1 57/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.