Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP2 | P08253 | 18/20 | 0.58 |
| ▸ | MMP1 | P03956 | 3/20 | 0.58 |
| ▸ | MMP8 | P22894 | 12/20 | 0.58 |
| ▸ | MMP9 | P14780 | 17/20 | 0.46 |
| ▸ | MMP14 | P50281 | 14/20 | 0.46 |
| ▸ | MMP3 | P08254 | 5/20 | 0.46 |
| ▸ | MMP7 | P09237 | 4/20 | 0.46 |
| ▸ | ADAM17 | P78536 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17039173 | 0.84 | MMP2 (0.55) | MMP2MMP1MMP8MMP9MMP14 | |
| SCHEMBL17026735 | 0.83 | MMP2 (0.82) | MMP2MMP1MMP8MMP9MMP14 | |
| SCHEMBL10187462 | 0.82 | MMP2 (0.67) | MMP2MMP1MMP8MMP9MMP14 | |
| SCHEMBL10238686 | 0.81 | MMP9 (0.71) | MMP2MMP1MMP8MMP9MMP14 | |
| SCHEMBL17026751 | 0.80 | MMP2 (0.56) | MMP2MMP1MMP9MMP14 | |
| SCHEMBL4292169 | 0.80 | MMP2 (0.67) | MMP2MMP1MMP8MMP9MMP14 | |
| SCHEMBL10187427 | 0.80 | MMP2 (0.60) | MMP2MMP1MMP8MMP9MMP14 | |
| SCHEMBL12717348 | 0.79 | MMP2 (0.69) | MMP2MMP1MMP8MMP9MMP14 | |
| SCHEMBL313439 | 0.78 | MMP2 (0.71) | MMP2MMP1MMP8MMP9MMP14 | |
| SCHEMBL14727900 | 0.76 | MMP2 (0.64) | MMP2MMP1MMP8MMP9MMP14 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3107905-A1 | SELECTIVE MATRIX METALLOPROTEINASE INHIBITORS | University of Notre Dame du Lac (US) | 2016-12-28 | — | — | EP | disclosed |
| WO-2016044844-A1 | ACCELERATION OF DIABETIC WOUND HEALING | UNIVERSITY OF NOTRE DAME DU LAC (US) | 2016-03-24 | — | — | WO | disclosed |
| WO-2015127302-A1 | SELECTIVE MATRIX METALLOPROTEINASE INHIBITORS | UNIVERSITY OF NOTRE DAME DU LAC (US) | 2015-08-27 | — | — | WO | disclosed |