Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP2 | P08253 | 12/20 | 0.55 |
| ▸ | MMP1 | P03956 | 2/20 | 0.55 |
| ▸ | MMP8 | P22894 | 4/20 | 0.54 |
| ▸ | MMP13 | P45452 | 1/20 | 0.45 |
| ▸ | CA1 | P00915 | 4/20 | 0.45 |
| ▸ | CA2 | P00918 | 4/20 | 0.45 |
| ▸ | MMP9 | P14780 | 10/20 | 0.44 |
| ▸ | MMP14 | P50281 | 7/20 | 0.43 |
| ▸ | CA12 | O43570 | 2/20 | 0.42 |
| ▸ | CA9 | Q16790 | 2/20 | 0.42 |
| ▸ | MMP3 | P08254 | 2/20 | 0.41 |
| ▸ | MMP7 | P09237 | 2/20 | 0.41 |
| ▸ | NAMPT | P43490 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17039177 | 0.85 | MMP2 (0.76) | MMP2MMP1MMP8MMP9MMP14 | |
| SCHEMBL17026726 | 0.84 | MMP2 (0.58) | MMP2MMP1MMP8MMP9MMP14 | |
| SCHEMBL17039176 | 0.82 | MMP2 (0.51) | MMP2MMP1MMP13MMP9MMP14 | |
| SCHEMBL10187427 | 0.77 | MMP2 (0.60) | MMP2MMP1MMP8MMP9MMP14 | |
| SCHEMBL10187462 | 0.76 | MMP2 (0.67) | MMP2MMP1MMP8MMP9MMP14 | |
| SCHEMBL12290472 | 0.75 | MMP2 (0.46) | MMP2MMP1MMP8MMP13MMP9 | |
| SCHEMBL313439 | 0.75 | MMP2 (0.71) | MMP2MMP1MMP8MMP9MMP14 | |
| SCHEMBL12717348 | 0.74 | MMP2 (0.69) | MMP2MMP1MMP8MMP9MMP14 | |
| SCHEMBL4374911 | 0.73 | L3MBTL1 (0.46) | MMP13CA1CA2CA12CA9 | |
| SCHEMBL14727900 | 0.73 | MMP2 (0.64) | MMP2MMP1MMP8MMP9MMP14 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10357546-B2 | Acceleration of diabetic wound healing | UNIVERSITY OF NOTRE DAME DU LAC (US) | 2019-07-23 | — | — | US | disclosed |
| US-9951035-B2 | Selective matrix metalloproteinase inhibitors | UNIVERSITY OF NOTRE DAME DU LAC (US) | 2018-04-24 | — | — | US | disclosed |
| US-20170274053-A1 | ACCELERATION OF DIABETIC WOUND HEALING | UNIVERSITY OF NOTRE DAME DU LAC (US) | 2017-09-28 | — | — | US | disclosed |
| US-20170190685-A1 | SELECTIVE MATRIX METALLOPROTEINASE INHIBITORS | UNIVERSITY OF NOTRE DAME DU LAC (US) | 2017-07-06 | — | — | US | disclosed |
| US-9604957-B2 | Selective matrix metalloproteinase inhibitors | UNIVERSITY OF NOTRE DAME DU LAC (US) | 2017-03-28 | — | — | US | disclosed |
| US-20170015647-A1 | SELECTIVE MATRIX METALLOPROTEINASE INHIBITORS | UNIVERSITY OF NOTRE DAME DU LAC (US) | 2017-01-19 | — | — | US | disclosed |
| WO-2016044844-A1 | ACCELERATION OF DIABETIC WOUND HEALING | UNIVERSITY OF NOTRE DAME DU LAC (US) | 2016-03-24 | — | — | WO | disclosed |
| WO-2015127302-A1 | SELECTIVE MATRIX METALLOPROTEINASE INHIBITORS | UNIVERSITY OF NOTRE DAME DU LAC (US) | 2015-08-27 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170274053-A1 | ACCELERATION OF DIABETIC WOUND HEALING | MMP8, MMP9, MMP1 | MMP2 6/4885MMP1 3/4885MMP8 1/4885 |
| US-20170190685-A1 | SELECTIVE MATRIX METALLOPROTEINASE INHIBITORS | MMP14, MMP9, MMP13 | MMP2 14/4885MMP1 18/4885MMP8 20/4885 |
| US-20170015647-A1 | SELECTIVE MATRIX METALLOPROTEINASE INHIBITORS | MMP14, MMP9, MMP13 | MMP2 14/4885MMP1 18/4885MMP8 20/4885 |
| US-10357546-B2 | Acceleration of diabetic wound healing | MMP8, MMP9, MMP1 | MMP2 6/4885MMP1 3/4885MMP8 1/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.