Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 7/20 | 0.68 |
| ▸ | MEN1 | O00255 | 7/20 | 0.68 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.68 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.68 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.68 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.68 |
| ▸ | HPGD | P15428 | 1/20 | 0.68 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.60 |
| ▸ | FNTA | P49354 | 1/20 | 0.60 |
| ▸ | FNTB | P49356 | 1/20 | 0.60 |
| ▸ | LMNA | P02545 | 2/20 | 0.56 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.54 |
| ▸ | PKM | P14618 | 1/20 | 0.54 |
| ▸ | CTBP2 | P56545 | 3/20 | 0.53 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.52 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.52 |
| ▸ | APAF1 | O14727 | 1/20 | 0.51 |
| ▸ | POLB | P06746 | 1/20 | 0.51 |
| ▸ | RECQL | P46063 | 1/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1754977 | 1.00 | MAPT (0.68) | MAPTMEN1KMT2ASMN1; SMN2KDM4E | |
| SCHEMBL8433947 | 0.83 | KMT2A (0.61) | MAPTMEN1KMT2ASMN1; SMN2KDM4E | |
| SCHEMBL20211099 | 0.81 | MEN1 (0.71) | MAPTMEN1KMT2ASMN1; SMN2KDM4E | |
| SCHEMBL7956840 | 0.81 | PKM (0.67) | MAPTMEN1KMT2ASMN1; SMN2KDM4E | |
| SCHEMBL8442871 | 0.81 | PKM (0.67) | MAPTMEN1KMT2ASMN1; SMN2KDM4E | |
| SCHEMBL7956839 | 0.81 | PKM (0.67) | MAPTMEN1KMT2ASMN1; SMN2KDM4E | |
| SCHEMBL29362070 | 0.81 | MEN1 (1.00) | MAPTMEN1KMT2ASMN1; SMN2KDM4E | |
| SCHEMBL27763159 | 0.81 | MEN1 (1.00) | MAPTMEN1KMT2ASMN1; SMN2KDM4E | |
| SCHEMBL125249 | 0.81 | MEN1 (1.00) | MAPTMEN1KMT2ASMN1; SMN2KDM4E | |
| Indole-3-Acetic Acid SCHEMBL26344 | 0.80 | MEN1 (0.75) | MAPTMEN1KMT2ASMN1; SMN2KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1806408-B1 | Process for producing amino acid derivatives from hydroxyimino acids | AJINOMOTO KK (JP) | 2012-04-18 | — | — | EP | claimed |
| US-8043836-B2 | Contacting Citrobacter/Escherichia and/or enzyme with a hydroxyimino acid; for biosynthesis of tryptophan | AJINOMOTO CO., INC. (JP) | 2011-10-25 | — | — | US | claimed |
| US-20080193984-A1 | Process For Producing Amino Acid Derivative From Hydroxyimino Acid | AJINOMOTO CO., INC. (JP) | 2008-08-14 | — | — | US | claimed |
| EP-1806408-A1 | PROCESS FOR PRODUCING AMINO ACID DERIVATIVE FROM HYDROXYIMINO ACID | Ajinomoto Co., Inc. (JP) | 2007-07-11 | — | — | EP | claimed |
| EP-1806408-B1 | Process for producing amino acid derivatives from hydroxyimino acids | AJINOMOTO KK (JP) | 2012-04-18 | — | — | EP | disclosed |
| US-8043836-B2 | Contacting Citrobacter/Escherichia and/or enzyme with a hydroxyimino acid; for biosynthesis of tryptophan | AJINOMOTO CO., INC. (JP) | 2011-10-25 | — | — | US | disclosed |
| US-8043836-B2 | Contacting Citrobacter/Escherichia and/or enzyme with a hydroxyimino acid; for biosynthesis of tryptophan | AJINOMOTO CO., INC. (JP) | 2011-10-25 | — | — | US | disclosed |
| US-20080193984-A1 | Process For Producing Amino Acid Derivative From Hydroxyimino Acid | AJINOMOTO CO., INC. (JP) | 2008-08-14 | — | — | US | disclosed |
| US-20080193984-A1 | Process For Producing Amino Acid Derivative From Hydroxyimino Acid | AJINOMOTO CO., INC. (JP) | 2008-08-14 | — | — | US | disclosed |
| EP-1806408-A1 | PROCESS FOR PRODUCING AMINO ACID DERIVATIVE FROM HYDROXYIMINO ACID | Ajinomoto Co., Inc. (JP) | 2007-07-11 | — | — | EP | disclosed |
| US-5607934-A | PREVENTING AND TREATING DISEASES CAUSED BY SUPEROXIDE RADICALS, NEPHRITIS | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1997-03-04 | — | — | US | disclosed |
| US-4194050-A | HYDROGENATING OXIMES HAVING AN ALPHA-HYDROGEN USING A RUTHENIUM CATALYST AND A CARBOXYLIC ANHYDRIDE | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1980-03-18 | — | — | US | disclosed |
| US-4137417-A | Process for producing an enamide | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1979-01-30 | — | — | US | disclosed |