Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 9/20 | 0.61 |
| ▸ | MEN1 | O00255 | 7/20 | 0.61 |
| ▸ | MAPT | P10636 | 6/20 | 0.61 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.61 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.61 |
| ▸ | HPGD | P15428 | 1/20 | 0.61 |
| ▸ | PKM | P14618 | 1/20 | 0.56 |
| ▸ | LMNA | P02545 | 2/20 | 0.55 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.55 |
| ▸ | FNTA | P49354 | 1/20 | 0.55 |
| ▸ | FNTB | P49356 | 1/20 | 0.55 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.51 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.51 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.51 |
| ▸ | APAF1 | O14727 | 1/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | RECQL | P46063 | 1/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.50 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1702738 | 0.83 | MAPT (0.68) | KMT2AMEN1MAPTKDM4ESMN1; SMN2 | |
| SCHEMBL1754977 | 0.83 | MAPT (0.68) | KMT2AMEN1MAPTKDM4ESMN1; SMN2 | |
| SCHEMBL8437808 | 0.82 | GPR84 (0.50) | KMT2AMEN1KDM4EALDH1A1HPGD | |
| SCHEMBL560186 | 0.81 | KMT2A (0.45) | KMT2AMEN1MAPTKDM4ESMN1; SMN2 | |
| SCHEMBL560187 | 0.81 | KMT2A (0.45) | KMT2AMEN1MAPTKDM4ESMN1; SMN2 | |
| SCHEMBL14000650 | 0.79 | PKM (0.52) | KMT2AMEN1MAPTKDM4ESMN1; SMN2 | |
| Indole-3-Acetic Acid SCHEMBL29272535 | 0.78 | MEN1 (0.73) | KMT2AMEN1MAPTKDM4ESMN1; SMN2 | |
| SCHEMBL20211099 | 0.77 | MEN1 (0.71) | KMT2AMEN1MAPTKDM4ESMN1; SMN2 | |
| SCHEMBL29466101 | 0.77 | PKM (0.73) | KMT2AMEN1MAPTKDM4ESMN1; SMN2 | |
| SCHEMBL584367 | 0.77 | PKM (0.73) | KMT2AMEN1MAPTKDM4ESMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1964835-A1 | Derivatives of psammaplin A, a method for their synthesis and their use for the prevention or treatment of cancer | Centre National de la Recherche Scientifique (FR) | 2008-09-03 | — | — | EP | disclosed |