SCHEMBL17028547

SCHEMBL17028547

CCOC(=O)CCCc1ccc(OCc2cc(F)ccc2Br)cn1

nearest known ligand 0.46

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
FFAR4 Q5NUL3 7/20 0.46
CYSLTR2 Q9NS75 2/20 0.41
CYSLTR1 Q9Y271 2/20 0.41
MAOB P27338 3/20 0.39
MMP1 P03956 3/20 0.39
FFAR1 O14842 2/20 0.38
POLB P06746 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17028609 0.86 FFAR4 (0.56) FFAR4FFAR1
SCHEMBL15265030 0.85 FFAR4 (0.49) FFAR4FFAR1
SCHEMBL17028569 0.83 FFAR4 (0.48) FFAR4FFAR1
SCHEMBL17028598 0.82 FFAR4 (0.54) FFAR4FFAR1
SCHEMBL15265930 0.81 FFAR4 (0.53) FFAR4MAOBFFAR1
SCHEMBL17028648 0.81 FFAR4 (0.73) FFAR4FFAR1
SCHEMBL17028696 0.80 FFAR4 (0.61) FFAR4FFAR1
SCHEMBL17028636 0.80 FFAR4 (0.69) FFAR4FFAR1
SCHEMBL3933040 0.79 FAAH (0.43) CYSLTR2CYSLTR1POLB
SCHEMBL17028546 0.78 FFAR4 (0.54) FFAR4CYSLTR2CYSLTR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3107901-B1 COMPOUNDS FOR USE AS GPR120 AGONISTS PIRAMAL ENTPR LTD (IN) 2020-04-01 EP disclosed
US-10227360-B2 Compounds for use as GPR120 agonists Piramal Enterprises Limited (IN) 2019-03-12 US disclosed
EP-3107901-A1 COMPOUNDS FOR USE AS GPR120 AGONISTS Piramal Enterprises Limited (IN) 2016-12-28 EP disclosed
US-20160347768-A1 COMPOUNDS FOR USE AS GPR120 AGONISTS Piramal Enterprises Limited (IN) 2016-12-01 US disclosed
WO-2015125085-A1 COMPOUNDS FOR USE AS GPR120 AGONISTS Piramal Enterprises Limited (IN) 2015-08-27 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10227360-B2 Compounds for use as GPR120 agonists GPR119, GPR55, GPR180 FFAR4 26/4885CYSLTR2 114/4885CYSLTR1 214/4885
US-20160347768-A1 COMPOUNDS FOR USE AS GPR120 AGONISTS GPR119, GPR55, GPR180 FFAR4 26/4885CYSLTR2 114/4885CYSLTR1 214/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.