SCHEMBL17028666

SCHEMBL17028666

c1ccc(OCC2(c3ccc(CC4CO4)cc3)CO2)cc1

nearest known ligand 0.46

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 1/20 0.46
HTR1A P08908 9/20 0.39
ADRA1A P35348 9/20 0.39
ADRA1D P25100 6/20 0.39
ADRA1B P35368 5/20 0.39
ALDH1A1 P00352 1/20 0.36
TP53 P04637 1/20 0.36
CYP3A4 P08684 1/20 0.36
TSHR P16473 1/20 0.36
SMN1; SMN2 Q16637 1/20 0.36
HIF1A Q16665 1/20 0.36
MEN1 O00255 1/20 0.35
KMT2A Q03164 1/20 0.35
CTSK P43235 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11264607 0.81 HTR1A (0.48) TDP1HTR1AADRA1AADRA1DADRA1B
SCHEMBL3480269 0.73 TDP1 (0.36) TDP1ALDH1A1TP53CYP3A4TSHR
SCHEMBL10187482 0.73 TDP1 (0.52) TDP1ALDH1A1TP53CYP3A4TSHR
SCHEMBL246844 0.71 TDP1 (0.54) TDP1HTR1AADRA1AADRA1DADRA1B
SCHEMBL873444 0.70 SLC6A2 (0.50) TDP1TSHRMEN1KMT2A
SCHEMBL51254 0.70 SLC6A2 (0.50) TDP1TSHRMEN1KMT2A
SCHEMBL2186411 0.70 SLC6A2 (0.50) TDP1TSHRMEN1KMT2A
Acrylic Acid SCHEMBL28032744 0.69 THRB (0.43) HTR1AADRA1AADRA1DADRA1BSMN1; SMN2
Water SCHEMBL27572757 0.68 SLC6A2 (0.48) TDP1MEN1KMT2A
Methane SCHEMBL28820455 0.68 SLC6A2 (0.48) TDP1MEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3107521-A1 ADHESIVE BONDING COMPOSITION AND USE THEREOF 3M Innovative Properties Company (US) 2016-12-28 EP disclosed
EP-3107523-A1 DENTAL COMPOSITION AND USE THEREOF 3M Innovative Properties Company (US) 2016-12-28 EP disclosed
WO-2015126862-A1 DENTAL COMPOSITION AND USE THEREOF 3M INNOVATIVE PROPERTIES COMPANY (US) 2015-08-27 WO disclosed
WO-2015126865-A1 ADHESIVE BONDING COMPOSITION AND USE THEREOF 3M INNOVATIVE PROPERTIES COMPANY (US) 2015-08-27 WO disclosed