Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.36 |
| ▸ | TP53 | P04637 | 4/20 | 0.35 |
| ▸ | TSHR | P16473 | 4/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.35 |
| ▸ | MAPT | P10636 | 3/20 | 0.35 |
| ▸ | HPGD | P15428 | 3/20 | 0.35 |
| ▸ | MEN1 | O00255 | 3/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.35 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.35 |
| ▸ | PKM | P14618 | 2/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.35 |
| ▸ | PPARG | P37231 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | ACACB | O00763 | 1/20 | 0.31 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL246844 | 0.83 | TDP1 (0.54) | TDP1TP53TSHRALDH1A1MEN1 | |
| SCHEMBL1352539 | 0.74 | ALDH1A1 (0.38) | TDP1TP53TSHRALDH1A1HIF1A | |
| SCHEMBL9247367 | 0.74 | TDP1 (0.63) | TDP1TP53TSHRALDH1A1MAPT | |
| SCHEMBL17028666 | 0.73 | TDP1 (0.46) | TDP1TP53TSHRALDH1A1MEN1 | |
| SCHEMBL1425747 | 0.71 | TDP1 (0.39) | TDP1TP53TSHRALDH1A1MAPT | |
| SCHEMBL6305833 | 0.71 | TDP1 (0.39) | TDP1TP53TSHRALDH1A1MAPT | |
| SCHEMBL14063027 | 0.71 | TDP1 (0.42) | TDP1TP53TSHRALDH1A1MAPT | |
| SCHEMBL131333 | 0.71 | TDP1 (0.38) | TDP1TP53TSHRALDH1A1MEN1 | |
| SCHEMBL20851114 | 0.70 | TDP1 (0.58) | TDP1TP53TSHRALDH1A1MAPT | |
| SCHEMBL27678116 | 0.70 | GAA (0.50) | TDP1TP53TSHRALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8389630-B2 | Curable composition | KANEKA CORPORATION (JP) | 2013-03-05 | — | — | US | disclosed |
| EP-1970408-B1 | CURABLE COMPOSITION | KANEKA CORP (JP) | 2011-12-28 | — | — | EP | disclosed |
| US-20100227949-A1 | CURABLE COMPOSITION | KANEKA CORPORATION (JP) | 2010-09-09 | — | — | US | disclosed |
| EP-1970408-A1 | CURABLE COMPOSITION | Kaneka Corporation (JP) | 2008-09-17 | — | — | EP | disclosed |