SCHEMBL17028704

SCHEMBL17028704

CCC(Cc1ccc(OCc2cc(F)ccc2-c2cccnc2)cc1)C(=O)O

nearest known ligand 0.56

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
FFAR4 Q5NUL3 14/20 0.56
FFAR1 O14842 4/20 0.56
MME P08473 1/20 0.45
ACE P12821 1/20 0.45
CPA1 P15085 1/20 0.45
ACE2 Q9BYF1 1/20 0.45
GPR132 Q9UNW8 1/20 0.45
PPARD Q03181 1/20 0.45
PPARA Q07869 1/20 0.45
KCNA5 P22460 1/20 0.44
KCNH2 Q12809 1/20 0.44
PPARG P37231 1/20 0.44
CYP11B1 P15538 1/20 0.43
CYP11B2 P19099 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15265915 0.83 FFAR4 (0.80) FFAR4FFAR1
SCHEMBL17028705 0.81 FFAR1 (0.51) FFAR4FFAR1KCNA5KCNH2
SCHEMBL15266060 0.81 FFAR4 (0.69) FFAR4FFAR1
SCHEMBL15265056 0.79 FFAR4 (0.61) FFAR4FFAR1
SCHEMBL17028627 0.79 PPARA (0.52) FFAR4FFAR1MMEACECPA1
SCHEMBL17028712 0.76 FFAR4 (0.59) FFAR4FFAR1
SCHEMBL17028731 0.73 FFAR4 (0.70) FFAR4FFAR1
SCHEMBL15266453 0.72 FFAR4 (0.80) FFAR4FFAR1
SCHEMBL15265028 0.72 FFAR4 (1.00) FFAR4FFAR1
SCHEMBL15265839 0.72 FFAR4 (0.81) FFAR4FFAR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3107901-B1 COMPOUNDS FOR USE AS GPR120 AGONISTS PIRAMAL ENTPR LTD (IN) 2020-04-01 EP disclosed
US-10227360-B2 Compounds for use as GPR120 agonists Piramal Enterprises Limited (IN) 2019-03-12 US disclosed
EP-3107901-A1 COMPOUNDS FOR USE AS GPR120 AGONISTS Piramal Enterprises Limited (IN) 2016-12-28 EP disclosed
US-20160347768-A1 COMPOUNDS FOR USE AS GPR120 AGONISTS Piramal Enterprises Limited (IN) 2016-12-01 US disclosed
WO-2015125085-A1 COMPOUNDS FOR USE AS GPR120 AGONISTS Piramal Enterprises Limited (IN) 2015-08-27 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10227360-B2 Compounds for use as GPR120 agonists GPR119, GPR55, GPR180 FFAR4 26/4885FFAR1 11/4885MME 3089/4885
US-20160347768-A1 COMPOUNDS FOR USE AS GPR120 AGONISTS GPR119, GPR55, GPR180 FFAR4 26/4885FFAR1 11/4885MME 3089/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.